# | Title | Journal | Year | Citations |
---|
1 | PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT | Journal of Biological Chemistry | 1951 | 284,654 |
2 | Protein measurement with the Folin phenol reagent | Journal of Biological Chemistry | 1951 | 242,821 |
3 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Analytical Biochemistry | 1976 | 215,588 |
4 | A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding | Analytical Biochemistry | 1976 | 92,750 |
5 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction | Analytical Biochemistry | 1987 | 58,438 |
6 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 | Genome Biology | 2014 | 58,325 |
7 | A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures | Physiologia Plantarum | 1962 | 56,749 |
8 | A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES | Journal of Biological Chemistry | 1957 | 55,906 |
9 | Hallmarks of Cancer: The Next Generation | Cell | 2011 | 52,242 |
10 | Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement | PLoS Medicine | 2009 | 50,671 |
11 | Fiji: an open-source platform for biological-image analysis | Nature Methods | 2012 | 47,818 |
12 | NIH Image to ImageJ: 25 years of image analysis | Nature Methods | 2012 | 46,756 |
13 | Fast gapped-read alignment with Bowtie 2 | Nature Methods | 2012 | 42,357 |
14 | A simple method for the isolation and purification of total lipides from animal tissues | Journal of Biological Chemistry | 1957 | 41,692 |
15 | MicroRNAs | Cell | 2004 | 32,446 |
16 | QIIME allows analysis of high-throughput community sequencing data | Nature Methods | 2010 | 31,818 |
17 | Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Analytical Biochemistry | 1987 | 27,111 |
18 | The Hallmarks of Cancer | Cell | 2000 | 24,832 |
19 | THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY | Journal of Cell Biology | 1963 | 24,709 |
20 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity | Analytical Biochemistry | 1983 | 24,572 |
21 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction | Analytical Biochemistry | 1979 | 22,890 |
22 | Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors | Cell | 2006 | 22,649 |
23 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | Journal of Biological Chemistry | 1985 | 20,165 |
24 | Measurement of protein using bicinchoninic acid | Analytical Biochemistry | 1985 | 19,774 |
25 | The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis | Journal of Biological Chemistry | 1969 | 19,178 |
26 | Floral dip: a simplified method forAgrobacterium-mediated transformation ofArabidopsis thaliana | Plant Journal | 1998 | 19,148 |
27 | DADA2: High-resolution sample inference from Illumina amplicon data | Nature Methods | 2016 | 18,691 |
28 | Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors | Cell | 2007 | 17,969 |
29 | MicroRNAs: Target Recognition and Regulatory Functions | Cell | 2009 | 17,802 |
30 | High resolution two-dimensional electrophoresis of proteins. | Journal of Biological Chemistry | 1975 | 17,755 |
31 | THE COLORIMETRIC DETERMINATION OF PHOSPHORUS | Journal of Biological Chemistry | 1925 | 17,551 |
32 | SciPy 1.0: fundamental algorithms for scientific computing in Python | Nature Methods | 2020 | 17,539 |
33 | A new generation of Ca2+ indicators with greatly improved fluorescence properties | Journal of Biological Chemistry | 1985 | 16,813 |
34 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis | Journal of Biological Chemistry | 1969 | 16,592 |
35 | HISAT: a fast spliced aligner with low memory requirements | Nature Methods | 2015 | 16,262 |
36 | SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor | Cell | 2020 | 16,161 |
37 | The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay | Analytical Biochemistry | 1996 | 16,000 |
38 | High resolution two-dimensional electrophoresis of proteins | Journal of Biological Chemistry | 1975 | 15,403 |
39 | Glutathione S-Transferases | Journal of Biological Chemistry | 1974 | 14,618 |
40 | DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION | Journal of Biological Chemistry | 1949 | 14,083 |
41 | Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. | Journal of Histochemistry and Cytochemistry | 1981 | 13,859 |
42 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement | Cytotherapy | 2006 | 13,839 |
43 | The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration | PLoS Medicine | 2009 | 13,772 |
44 | Differential expression analysis for sequence count data | Genome Biology | 2010 | 13,707 |
45 | jModelTest 2: more models, new heuristics and parallel computing | Nature Methods | 2012 | 13,416 |
46 | UPARSE: highly accurate OTU sequences from microbial amplicon reads | Nature Methods | 2013 | 13,193 |
47 | Phosphorus Assay in Column Chromatography | Journal of Biological Chemistry | 1959 | 12,077 |
48 | Mapping and quantifying mammalian transcriptomes by RNA-Seq | Nature Methods | 2008 | 12,050 |
49 | Matrix Elasticity Directs Stem Cell Lineage Specification | Cell | 2006 | 11,769 |
50 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa | Analytical Biochemistry | 1987 | 11,692 |
51 | A series of normal stages in the development of the chick embryo | Journal of Morphology | 1951 | 11,689 |
52 | A method and server for predicting damaging missense mutations | Nature Methods | 2010 | 11,491 |
53 | Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal | Science Signaling | 2013 | 11,344 |
54 | The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 | Cell | 1993 | 11,149 |
55 | The Hallmarks of Aging | Cell | 2013 | 10,992 |
56 | Superoxide Dismutase | Journal of Biological Chemistry | 1969 | 10,959 |
57 | Glutathione S-transferases. The first enzymatic step in mercapturic acid formation | Journal of Biological Chemistry | 1974 | 10,908 |
58 | Free radicals and antioxidants in normal physiological functions and human disease | International Journal of Biochemistry and Cell Biology | 2007 | 10,891 |
59 | Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets | Cell | 2005 | 10,880 |
60 | A genetic model for colorectal tumorigenesis | Cell | 1990 | 10,831 |
61 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids | Analytical Biochemistry | 1982 | 10,819 |
62 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells | Nature Cell Biology | 2007 | 10,558 |
63 | Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels | Analytical Biochemistry | 1971 | 10,405 |
64 | The Carbon Monoxide-binding Pigment of Liver Microsomes | Journal of Biological Chemistry | 1964 | 10,318 |
65 | Determination of serum proteins by means of the biuret reaction | Journal of Biological Chemistry | 1949 | 10,253 |
66 | Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities | Molecular Cell | 2010 | 10,215 |
67 | Apoptosis: A Review of Programmed Cell Death | Toxicologic Pathology | 2007 | 10,063 |
68 | IMPROVEMENTS IN EPOXY RESIN EMBEDDING METHODS | Journal of Cell Biology | 1961 | 9,922 |
69 | Phosphorus assay in column chromatography | Journal of Biological Chemistry | 1959 | 9,901 |
70 | Pathogen Recognition and Innate Immunity | Cell | 2006 | 9,878 |
71 | Integrins: Versatility, modulation, and signaling in cell adhesion | Cell | 1992 | 9,858 |
72 | Comprehensive Integration of Single-Cell Data | Cell | 2019 | 9,755 |
73 | Mechanisms of Salinity Tolerance | Annual Review of Plant Biology | 2008 | 9,628 |
74 | ModelFinder: fast model selection for accurate phylogenetic estimates | Nature Methods | 2017 | 9,486 |
75 | A simple technique for quantitation of low levels of DNA damage in individual cells | Experimental Cell Research | 1988 | 9,283 |
76 | REACTIVE OXYGEN SPECIES: Metabolism, Oxidative Stress, and Signal Transduction | Annual Review of Plant Biology | 2004 | 9,281 |
77 | Chromatin Modifications and Their Function | Cell | 2007 | 9,258 |
78 | A Film Detection Method for Tritium-Labelled Proteins and Nucleic Acids in Polyacrylamide Gels | FEBS Journal | 1974 | 9,250 |
79 | Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. | Molecular and Cellular Biology | 1982 | 9,217 |
80 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. | Journal of Cell Biology | 1992 | 9,185 |
81 | A PHOTOMETRIC ADAPTATION OF THE SOMOGYI METHOD FOR THE DETERMINATION OF GLUCOSE | Journal of Biological Chemistry | 1944 | 9,042 |
82 | Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death | Cell | 2012 | 9,007 |
83 | THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE | Journal of Biological Chemistry | 1964 | 8,804 |
84 | Fast and sensitive protein alignment using DIAMOND | Nature Methods | 2015 | 8,761 |
85 | “Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A | Analytical Biochemistry | 1981 | 8,736 |
86 | LIGAND: A versatile computerized approach for characterization of ligand-binding systems | Analytical Biochemistry | 1980 | 8,732 |
87 | Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein) | Journal of Biological Chemistry | 1969 | 8,725 |
88 | Nutrient requirements of suspension cultures of soybean root cells | Experimental Cell Research | 1968 | 8,681 |
89 | Epithelial-Mesenchymal Transitions in Development and Disease | Cell | 2009 | 8,592 |
90 | A simplification of the protein assay method of Lowry et al. which is more generally applicable | Analytical Biochemistry | 1977 | 8,587 |
91 | SignalP 4.0: discriminating signal peptides from transmembrane regions | Nature Methods | 2011 | 8,521 |
92 | Immunity, Inflammation, and Cancer | Cell | 2010 | 8,516 |
93 | Robust enumeration of cell subsets from tissue expression profiles | Nature Methods | 2015 | 8,460 |
94 | Projections of Global Mortality and Burden of Disease from 2002 to 2030 | PLoS Medicine | 2006 | 8,440 |
95 | Enzymatic assembly of DNA molecules up to several hundred kilobases | Nature Methods | 2009 | 8,117 |
96 | WAF1, a potential mediator of p53 tumor suppression | Cell | 1993 | 8,091 |
97 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies | PLoS Medicine | 2007 | 7,961 |
98 | A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes | Cell | 1993 | 7,960 |
99 | Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase | FEBS Journal | 1974 | 7,903 |
100 | The Molecular Signatures Database Hallmark Gene Set Collection | Cell Systems | 2015 | 7,719 |