8,993
Journals
19.3M
Articles
521.6M
Citations
1.9M
Authors

Most Cited Articles of Life Sciences in 2011

TitleJournalYearCitations
Hallmarks of cancer: the next generationCell201139.8K
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methodsMolecular Biology and Evolution201132.7K
Full-length transcriptome assembly from RNA-Seq data without a reference genomeNature Biotechnology201111.8K
VESTA 3for three-dimensional visualization of crystal, volumetric and morphology dataJournal of Applied Crystallography201111K
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genomeBMC Bioinformatics20119.6K
UCHIME improves sensitivity and speed of chimera detectionBioinformatics20119.4K
Overview of the CCP4 suite and current developmentsActa Crystallographica Section D: Biological Crystallography20118.8K
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal OmegaMolecular Systems Biology20118.6K
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer's and Dementia20118.2K
Integrative genomics viewerNature Biotechnology20117.5K
A framework for variation discovery and genotyping using next-generation DNA sequencing dataNature Genetics20117.3K
SignalP 4.0: discriminating signal peptides from transmembrane regionsNature Methods20116.9K
FLASH: fast length adjustment of short reads to improve genome assembliesBioinformatics20116.8K
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteriaAnnals of Neurology20116.5K
Metagenomic biomarker discovery and explanationGenome Biology20116.3K
The variant call format and VCFtoolsBioinformatics20116.2K
Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guidelineJournal of Clinical Endocrinology and Metabolism20115.9K
REFMAC5 for the refinement of macromolecular crystal structuresActa Crystallographica Section D: Biological Crystallography20115.7K
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer's and Dementia20115.6K
pROC: an open-source package for R and S+ to analyze and compare ROC curvesBMC Bioinformatics20115.2K
Foodborne illness acquired in the United States--major pathogensEmerging Infectious Diseases20115K
FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological dataComputational Intelligence and Neuroscience20114.7K
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tablesJournal of Clinical Epidemiology20114.5K
Multiple imputation using chained equations: Issues and guidance for practiceStatistics in Medicine20114.4K
A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?Cell20114.2K