| # | Title | Journal | Year | Citations |
|---|
| 1 | Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Journal of Immunological Methods | 1983 | 47,133 |
| 2 | The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis | Arthritis and Rheumatism | 1988 | 18,339 |
| 3 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement | Cytotherapy | 2006 | 13,839 |
| 4 | The 1982 revised criteria for the classification of systemic lupus erythematosus | Arthritis and Rheumatism | 1982 | 12,163 |
| 5 | Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus | Arthritis and Rheumatism | 1997 | 9,579 |
| 6 | Radiological Assessment of Osteo-Arthrosis | Annals of the Rheumatic Diseases | 1957 | 9,474 |
| 7 | The american college of rheumatology 1990 criteria for the classification of fibromyalgia | Arthritis and Rheumatism | 1990 | 7,828 |
| 8 | The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia | Blood | 2016 | 7,429 |
| 9 | Exploring the full spectrum of macrophage activation | Nature Reviews Immunology | 2008 | 7,332 |
| 10 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors | Nature Immunology | 2010 | 7,320 |
| 11 | Toll-like receptor signalling | Nature Reviews Immunology | 2004 | 7,318 |
| 12 | TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties | Annual Review of Immunology | 1989 | 7,131 |
| 13 | STUDIES OF MARINE PLANKTONIC DIATOMS: I. CYCLOTELLA NANA HUSTEDT, AND DETONULA CONFERVACEA (CLEVE) GRAN. | Canadian Journal of Microbiology | 1962 | 6,913 |
| 14 | INNATEIMMUNERECOGNITION | Annual Review of Immunology | 2002 | 6,871 |
| 15 | 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative | Arthritis and Rheumatism | 2010 | 6,781 |
| 16 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Nature Immunology | 2003 | 6,653 |
| 17 | A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments] | Blood | 1994 | 6,150 |
| 18 | The 2016 revision of the World Health Organization classification of lymphoid neoplasms | Blood | 2016 | 5,965 |
| 19 | Immunobiology of Dendritic Cells | Annual Review of Immunology | 2000 | 5,918 |
| 20 | The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 | Nature Microbiology | 2020 | 5,799 |
| 21 | THE NF-κB AND IκB PROTEINS: New Discoveries and Insights | Annual Review of Immunology | 1996 | 5,787 |
| 22 | INTERLEUKIN-10AND THEINTERLEUKIN-10 RECEPTOR | Annual Review of Immunology | 2001 | 5,712 |
| 23 | Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee | Arthritis and Rheumatism | 1986 | 5,701 |
| 24 | Myeloid-derived suppressor cells as regulators of the immune system | Nature Reviews Immunology | 2009 | 5,655 |
| 25 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. | Journal of Immunology | 1986 | 5,495 |
| 26 | Alternative activation of macrophages | Nature Reviews Immunology | 2003 | 5,300 |
| 27 | The chemokine system in diverse forms of macrophage activation and polarization | Trends in Immunology | 2004 | 5,272 |
| 28 | TOLL-LIKERECEPTORS | Annual Review of Immunology | 2003 | 5,168 |
| 29 | Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis | Arthritis and Rheumatism | 1995 | 5,078 |
| 30 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins | Journal of Immunology | 1986 | 4,993 |
| 31 | Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee | Journal of Rheumatology | 1988 | 4,991 |
| 32 | Evaluation of Diagnostic Criteria for Ankylosing Spondylitis | Arthritis and Rheumatism | 1984 | 4,902 |
| 33 | NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses | Annual Review of Immunology | 1998 | 4,878 |
| 34 | Preliminary criteria for the classification of systemic sclerosis (scleroderma) | Arthritis and Rheumatism | 1980 | 4,858 |
| 35 | 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides | Arthritis and Rheumatism | 2013 | 4,839 |
| 36 | Oncology Meets Immunology: The Cancer-Immunity Cycle | Immunity | 2013 | 4,815 |
| 37 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. | Journal of Experimental Medicine | 1994 | 4,727 |
| 38 | Function and Activation of NF-kappaB in the Immune System | Annual Review of Immunology | 1994 | 4,653 |
| 39 | Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines | Immunity | 2014 | 4,638 |
| 40 | A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V | Journal of Immunological Methods | 1995 | 4,628 |
| 41 | Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group | Annals of the Rheumatic Diseases | 2002 | 4,586 |
| 42 | Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes | Trends in Immunology | 2002 | 4,494 |
| 43 | PD-1 and Its Ligands in Tolerance and Immunity | Annual Review of Immunology | 2008 | 4,462 |
| 44 | The Dendritic Cell System and its Role in Immunogenicity | Annual Review of Immunology | 1991 | 4,442 |
| 45 | Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. | Journal of Immunology | 1995 | 4,432 |
| 46 | Exosomes: composition, biogenesis and function | Nature Reviews Immunology | 2002 | 4,401 |
| 47 | Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation | Journal of Experimental Medicine | 2000 | 4,394 |
| 48 | Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood | 2017 | 4,375 |
| 49 | A rapid method for the isolation of functional thymus-derived murine lymphocytes | European Journal of Immunology | 1973 | 4,373 |
| 50 | Tolerance, Danger, and the Extended Family | Annual Review of Immunology | 1994 | 4,369 |
| 51 | Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity | Annual Review of Immunology | 2000 | 4,367 |
| 52 | Monocyte and macrophage heterogeneity | Nature Reviews Immunology | 2005 | 4,366 |
| 53 | Rapid colorimetric assay for cell growth and survival | Journal of Immunological Methods | 1986 | 4,360 |
| 54 | A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry | Journal of Immunological Methods | 1991 | 4,314 |
| 55 | Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases | Journal of Immunology | 1995 | 4,293 |
| 56 | Cancer immunoediting: from immunosurveillance to tumor escape | Nature Immunology | 2002 | 4,290 |
| 57 | IL-17 and Th17 Cells | Annual Review of Immunology | 2009 | 4,231 |
| 58 | Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 | Journal of Experimental Medicine | 2003 | 4,213 |
| 59 | Toll-like receptors: critical proteins linking innate and acquired immunity | Nature Immunology | 2001 | 4,209 |
| 60 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Nature Immunology | 2005 | 4,106 |
| 61 | Derivation of the sledai. A disease activity index for lupus patients | Arthritis and Rheumatism | 1992 | 4,086 |
| 62 | International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes | Blood | 1997 | 4,078 |
| 63 | Protective and pathogenic functions of macrophage subsets | Nature Reviews Immunology | 2011 | 4,050 |
| 64 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II | Arthritis and Rheumatism | 2008 | 4,029 |
| 65 | PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES | Journal of Experimental Medicine | 1954 | 4,028 |
| 66 | Human mesenchymal stem cells modulate allogeneic immune cell responses | Blood | 2005 | 4,024 |
| 67 | Neutrophil recruitment and function in health and inflammation | Nature Reviews Immunology | 2013 | 3,964 |
| 68 | Measurement of patient outcome in arthritis | Arthritis and Rheumatism | 1980 | 3,946 |
| 69 | The gut microbiota shapes intestinal immune responses during health and disease | Nature Reviews Immunology | 2009 | 3,946 |
| 70 | Foreign body reaction to biomaterials | Seminars in Immunology | 2008 | 3,942 |
| 71 | Biologic basis for interleukin-1 in disease | Blood | 1996 | 3,893 |
| 72 | A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 | Nature Immunology | 2005 | 3,869 |
| 73 | The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes | Blood | 2009 | 3,864 |
| 74 | Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus | Arthritis and Rheumatism | 2012 | 3,838 |
| 75 | The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak | Journal of Autoimmunity | 2020 | 3,834 |
| 76 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 77 | Nomenclature of Systemic Vasculitides | Arthritis and Rheumatism | 1994 | 3,714 |
| 78 | NITRIC OXIDE AND MACROPHAGE FUNCTION | Annual Review of Immunology | 1997 | 3,707 |
| 79 | The Immune Landscape of Cancer | Immunity | 2018 | 3,706 |
| 80 | Toll-like receptor control of the adaptive immune responses | Nature Immunology | 2004 | 3,662 |
| 81 | Sex differences in immune responses | Nature Reviews Immunology | 2016 | 3,615 |
| 82 | Chemokines | Immunity | 2000 | 3,582 |
| 83 | Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray | Blood | 2004 | 3,574 |
| 84 | Toll-like receptors and innate immunity | Nature Reviews Immunology | 2001 | 3,573 |
| 85 | NF-κB regulation in the immune system | Nature Reviews Immunology | 2002 | 3,568 |
| 86 | Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. | Journal of Experimental Medicine | 1991 | 3,556 |
| 87 | IL-23 drives a pathogenic T cell population that induces autoimmune inflammation | Journal of Experimental Medicine | 2005 | 3,550 |
| 88 | Getting to the site of inflammation: the leukocyte adhesion cascade updated | Nature Reviews Immunology | 2007 | 3,547 |
| 89 | WHO-EORTC classification for cutaneous lymphomas | Blood | 2005 | 3,529 |
| 90 | Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus | Journal of Virology | 2020 | 3,520 |
| 91 | Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis | Journal of Innate Immunity | 2016 | 3,509 |
| 92 | Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. | Journal of Experimental Medicine | 1992 | 3,473 |
| 93 | The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses | Nature Immunology | 2004 | 3,433 |
| 94 | The expanding universe of T-cell subsets: Th1, Th2 and more | Trends in Immunology | 1996 | 3,410 |
| 95 | Membrane vesicles as conveyors of immune responses | Nature Reviews Immunology | 2009 | 3,386 |
| 96 | Une micro-méthode de l’immuno-électrophorèse | International Archives of Allergy and Immunology | 1955 | 3,381 |
| 97 | Adipokines in inflammation and metabolic disease | Nature Reviews Immunology | 2011 | 3,378 |
| 98 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 99 | Oxidative Stress and Antioxidant Defense | World Allergy Organization Journal | 2012 | 3,353 |
| 100 | The trinity of COVID-19: immunity, inflammation and intervention | Nature Reviews Immunology | 2020 | 3,347 |
