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Most Cited Articles of Metabolic Engineering in 2012

TitleJournalYearCitations
Synthetic biology and the development of tools for metabolic engineeringMetabolic Engineering2012316
Cell-free synthetic biology: thinking outside the cellMetabolic Engineering2012298
The future of metabolic engineering and synthetic biology: towards a systematic practiceMetabolic Engineering2012240
Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiaeMetabolic Engineering2012206
Spatial organization of enzymes for metabolic engineeringMetabolic Engineering2012177
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch modeMetabolic Engineering2012174
The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acidsMetabolic Engineering2012170
Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platformMetabolic Engineering2012157
Enhancing fatty acid production by the expression of the regulatory transcription factor FadRMetabolic Engineering2012132
Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathwayMetabolic Engineering2012120
Expanding the chemical palate of cells by combining systems biology and metabolic engineeringMetabolic Engineering2012119
Designing and creating a modularized synthetic pathway in cyanobacterium Synechocystis enables production of acetone from carbon dioxideMetabolic Engineering2012119
High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switchMetabolic Engineering2012117
Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathwaysMetabolic Engineering2012113
A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcoholsMetabolic Engineering2012112
On metabolic shift to lactate consumption in fed-batch culture of mammalian cellsMetabolic Engineering2012109
Remodeling the isoprenoid pathway in tobacco by expressing the cytoplasmic mevalonate pathway in chloroplastsMetabolic Engineering2012106
Parts plus pipes: synthetic biology approaches to metabolic engineeringMetabolic Engineering2012104
Production and characterization of poly(3-hydroxypropionate-co-4-hydroxybutyrate) with fully controllable structures by recombinant Escherichia coli containing an engineered pathwayMetabolic Engineering2012102
Mathematical optimization applications in metabolic networksMetabolic Engineering2012100
A molecular transporter engineering approach to improving xylose catabolism in Saccharomyces cerevisiaeMetabolic Engineering201299
Visualizing evolution in real time to determine the molecular mechanisms of n-butanol tolerance in Escherichia coliMetabolic Engineering201291
A dynamic metabolite valve for the control of central carbon metabolismMetabolic Engineering201287
Metabolic engineering of D-xylose pathway in Clostridium beijerinckii to optimize solvent production from xylose mother liquidMetabolic Engineering201286
An integrated computational and experimental study for overproducing fatty acids in Escherichia coliMetabolic Engineering201286