| Hallmarks of cancer: the next generation | Cell | 2011 | 39.8K |
| MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods | Molecular Biology and Evolution | 2011 | 32.7K |
| Full-length transcriptome assembly from RNA-Seq data without a reference genome | Nature Biotechnology | 2011 | 11.8K |
| RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome | BMC Bioinformatics | 2011 | 9.6K |
| UCHIME improves sensitivity and speed of chimera detection | Bioinformatics | 2011 | 9.4K |
| Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega | Molecular Systems Biology | 2011 | 8.6K |
| The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 8.2K |
| Integrative genomics viewer | Nature Biotechnology | 2011 | 7.5K |
| A framework for variation discovery and genotyping using next-generation DNA sequencing data | Nature Genetics | 2011 | 7.3K |
| SignalP 4.0: discriminating signal peptides from transmembrane regions | Nature Methods | 2011 | 6.9K |
| FLASH: fast length adjustment of short reads to improve genome assemblies | Bioinformatics | 2011 | 6.8K |
| Metagenomic biomarker discovery and explanation | Genome Biology | 2011 | 6.3K |
| The variant call format and VCFtools | Bioinformatics | 2011 | 6.2K |
| The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 5.6K |
| pROC: an open-source package for R and S+ to analyze and compare ROC curves | BMC Bioinformatics | 2011 | 5.2K |
| Foodborne illness acquired in the United States--major pathogens | Emerging Infectious Diseases | 2011 | 5K |
| FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data | Computational Intelligence and Neuroscience | 2011 | 4.7K |
| GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables | Journal of Clinical Epidemiology | 2011 | 4.5K |
| Multiple imputation using chained equations: Issues and guidance for practice | Statistics in Medicine | 2011 | 4.4K |
| A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? | Cell | 2011 | 4.2K |
| Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 4.2K |
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Nature Cell Biology | 2011 | 4.2K |
| The organization of the human cerebral cortex estimated by intrinsic functional connectivity | Journal of Neurophysiology | 2011 | 4K |
| MoS2 nanoparticles grown on graphene: an advanced catalyst for the hydrogen evolution reaction | Journal of the American Chemical Society | 2011 | 4K |
| GRADE guidelines: 3. Rating the quality of evidence | Journal of Clinical Epidemiology | 2011 | 3.9K |
