| Gene ontology: tool for the unification of biology. The Gene Ontology Consortium | Nature Genetics | 2000 | 25.6K |
| The Protein Data Bank | Nucleic Acids Research | 2000 | 24.1K |
| Inference of population structure using multilocus genotype data | Genetics | 2000 | 22.3K |
| The hallmarks of cancer | Cell | 2000 | 20.9K |
| KEGG: kyoto encyclopedia of genes and genomes | Nucleic Acids Research | 2000 | 15.7K |
| Primer3 on the WWW for general users and for biologist programmers | Methods in Molecular Biology | 2000 | 8.6K |
| TCS: a computer program to estimate gene genealogies | Molecular Ecology | 2000 | 7.6K |
| Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis | Molecular Biology and Evolution | 2000 | 6.9K |
| PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals | Circulation | 2000 | 6.6K |
| Voxel-based morphometry--the methods | NeuroImage | 2000 | 6.6K |
| EMBOSS: the European Molecular Biology Open Software Suite | Trends in Genetics | 2000 | 6.4K |
| Emotion circuits in the brain | Annual Review of Neuroscience | 2000 | 6.1K |
| Chlorophyll fluorescence—a practical guide | Journal of Experimental Botany | 2000 | 5.7K |
| T-Coffee: A novel method for fast and accurate multiple sequence alignment | Journal of Molecular Biology | 2000 | 5.3K |
| Immunobiology of dendritic cells | Annual Review of Immunology | 2000 | 5.3K |
| Loop-mediated isothermal amplification of DNA | Nucleic Acids Research | 2000 | 5.1K |
| LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | EMBO Journal | 2000 | 5K |
| Lipid rafts and signal transduction | Nature Reviews Molecular Cell Biology | 2000 | 5K |
| Cognitive and emotional influences in anterior cingulate cortex | Trends in Cognitive Sciences | 2000 | 4.9K |
| Independent component analysis: algorithms and applications | Neural Networks | 2000 | 4.9K |
| Predictive habitat distribution models in ecology | Ecological Modelling | 2000 | 4.8K |
| A review of chitin and chitosan applications | Reactive and Functional Polymers | 2000 | 4.3K |
| The versatility and universality of calcium signalling | Nature Reviews Molecular Cell Biology | 2000 | 4.3K |
| The adolescent brain and age-related behavioral manifestations | Neuroscience and Biobehavioral Reviews | 2000 | 4K |
| Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Annual Review of Immunology | 2000 | 4K |
