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Phenytoin and Other Hydantoins

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Atlas of Epilepsies

Chemical Structure and When it was Licensed

Structure of a Hydantoin Molecule

This is the basic structure for a hydantoin molecule. Phenytoin, ethotoin, mephenytoin, and fosphenytoin all fall into the category hydantoin molecules and have been used as antiepileptic agents (Fig. 277-1 ).

Figure 277-1
figure 1_277 figure 1_277

Structure of a hydantoin molecule

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Abbreviations

ANDA:

Abbreviated new drug application

FDA:

Food and drug administration

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Nemire, R.E., Ramsay, R.E. (2010). Phenytoin and Other Hydantoins. In: Panayiotopoulos, C.P. (eds) Atlas of Epilepsies. Springer, London. https://doi.org/10.1007/978-1-84882-128-6_277

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