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Karel Kostev and Matthias Kalder declares that they have no conflict of interest.
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Research involving human participants/informed consent
German law allows the use of anonymous electronic medical records for research purposes under certain conditions. According to this legislation, it is not necessary to obtain informed consent from patients or approval from a medical ethics committee for this type of observational study that contains no directly identifiable data. Because patients were only queried as aggregates and no protected health information was available for queries, no IRB approval was required for the use of this database or the completion of this study.
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Kostev, K., Kalder, M. 20-year risk of breast cancer recurrence. Breast Cancer Res Treat 168, 765–766 (2018). https://doi.org/10.1007/s10549-017-4636-3
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DOI: https://doi.org/10.1007/s10549-017-4636-3