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Diffusion-weighed MR imaging of pancreatic carcinoma

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Abstract

Purpose

The aim of this study was to demonstrate the feasibility of body diffusion-weighted (DW) MR imaging in the evaluation of a pancreatic carcinoma.

Material and methods

In nine normal volunteers and in eight patients with pancreatic carcinoma, DW images were obtained on the axial plane scanning with a multisection spin-echo-type single-shot echo planar sequence with a body coil. Moreover, we measured the apparent diffusion coefficient (ADC) value in a circular region of interest (ROI) within the normal pancreas, pancreatic carcinoma, and tumor-associated chronic pancreatitis.

Results

On the DW images, all eight carcinomas were clearly shown as high signal intensity relative to the surrounding tissue. The ADC value (×10−3 mm2/s) in the carcinoma was 1.44 ± 0.20, which was significantly lower compared to that of normal pancreas (1.90 ± 0.06) and tumor-associated chronic pancreatitis (2.31 ± 0.18).

Conclusion

Diffusion-weighted (DW) images can be helpful in detecting the pancreatic carcinoma and accessing the extent of the tumor.

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Authors and Affiliations

  1. Department of Radiology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki City, Osaka, 569-8686, Japan

    M. Matsuki, Y. Inada, G. Nakai, F. Tatsugami, M. Tanikake & I. Narabayashi

  2. Second Internal Medicine, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki City, Osaka, 569-8686, Japan

    D. Masuda & Y. Arisaka

  3. General and Gastrointestinal Surgery, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki City, Osaka, 569-8686, Japan

    K. Takaori & N. Tanigawa

Authors
  1. M. Matsuki
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  2. Y. Inada
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  3. G. Nakai
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  4. F. Tatsugami
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  5. M. Tanikake
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  6. I. Narabayashi
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  7. D. Masuda
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  8. Y. Arisaka
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  9. K. Takaori
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  10. N. Tanigawa
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Corresponding author

Correspondence to M. Matsuki.

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Matsuki, M., Inada, Y., Nakai, G. et al. Diffusion-weighed MR imaging of pancreatic carcinoma. Abdom Imaging 32, 481–483 (2007). https://doi.org/10.1007/s00261-007-9192-6

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  • DOI: https://doi.org/10.1007/s00261-007-9192-6

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