Vet Med - Czech, 2001, 46(6):169-171 | DOI: 10.17221/7876-VETMED

Potential hazard of simultaneous occurrence of aflatoxin B-1 and ochratoxin AOriginal Paper

M. Sedmíková, H. Reisnerová, Z. Dufková, I. Bárta, F. Jílek
1 Department of Veterinary Science, Czech University of Agriculture, Prague, Czech Republic
2 Division of General Biology and Genetics, Charles University,
3 rd Faculty of Medicine, Prague, Czech Republic

Contents of aflatoxin B1 (AFB1) and ochratoxin A (OA) in the samples of wheat and barley were detected by RIA method. Average contents of AFB1 in the samples of wheat and barley were 2.4 µg/kg and 2.2 µg/kg, respectively. Average contents of OA in the samples of wheat and barley were 3.1 µg/kg and 2.4 µg/kg, respectively. The contents of mycotoxins corresponded to the allowed limits in food. During the studies of mutagenic activity of mycotoxins and their combinations by means of Ames test it was found that OA could increase the mutagenicity of AFB1 in the case of their simultaneous occurrence in the same substrate.

Keywords: mycotoxins; residua; cereals; Ames test; mutagenicity

Published: June 30, 2001  Show citation

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Sedmíková M, Reisnerová H, Dufková Z, Bárta I, Jílek F. Potential hazard of simultaneous occurrence of aflatoxin B-1 and ochratoxin A. Vet Med-Czech. 2001;46(6):169-171. doi: 10.17221/7876-VETMED.
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