Abstract
Computed tomography (CT) of the chest is the cornerstone of the diagnosis and staging of lung cancer. The advantages of CT in imaging the thorax are its cross-sectional format, superior density resolution, and wide dynamic range. Today’s CT scanners combine fast acquisition, fast data reconstruction, and very high spatial resolution. The aim of the current chapter is to review the role of contrast-enhanced MDCT in the diagnosis and staging of lung cancer and characterization of solitary pulmonary nodules.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- LLL:
-
Left lower lobe
- LUL:
-
Left upper lobe
- NSCLC:
-
Non-small cell lung cancer
- RECIST:
-
Response evaluation criteria in solid tumors
- RLL:
-
Right lower lobe
- RML:
-
Right middle lobe
- RUL:
-
Right upper lobe
References
Boland GW et al (1998) Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature. AJR Am J Roentgenol 171:201–204
Callister MEJ, Baldwin DR, Akram AR, Barnard S, Cane P, Draffan J, Franks K, Gleeson F, Graham R, Malhotra P, Prokop M, Rodger K, Subesinghe M, Waller D, Woolhouse I, British Thoracic Society Pulmonary Nodule Guideline Development Group; British Thoracic Society Standards of Care Committee (2015) British Thoracic Society guidelines for the investigation and management of pulmonary nodules. Thorax. https://doi.org/10.1136/thoraxjnl-2015-207168
Caoili EM et al (2000) Delayed enhanced CT of lipid-poor adrenal adenomas. AJR Am J Roentgenol 175:1411–1415
Coche E (2016) Evaluation of lung tumor response to therapy: current and emerging techniques. Diagn Interv Imaging 97:1053–1065
Dales RE, Stark RM, Raman S (1990) Computed tomography to stage lung cancer. Approaching a controversy using meta-analysis. Am Rev Respir Dis 141:1096–1101
de Hoop B, van Ginneken B, Gietema H, Prokop M (2012) Pulmonary perifissural nodules on CT scans: rapid growth is not a predictor of malignancy. Radiology 265(2):611–616
Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT (2017) The eighth edition lung cancer stage classification. Chest 151(1):193–203
Dwamena BA, Sonnad SS, Angobaldo JO, Wahl RL (1999) Metastases from non-small cell lung cancer: mediastinal staging in the 1990s—meta-analytic comparison of PET and CT. Radiology 213:530–536
Erasmus JJ, Connolly JE, McAdams HP et al (2000a) Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics 20:43–58
Erasmus JJ, McAdams HP, Connolly JE (2000b) Solitary pulmonary nodules: Part II. Evaluation of the indeterminate nodule. Radiographics 20:43–58
Klein JS, Salomon G, Stewart EA (1996) Transthoracic needle biopsy with a coaxially placed 20-gauge automated cutting needle: results in 122 patients. Radiology 198:715–720
Korobkin M et al (1996) Differentiation of adrenal adenomas from nonadenomas using CT attenuation values. AJR Am J Roentgenol 166:531–536
MacMahon H et al (2017) Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017. Radiology. https://doi.org/10.1148/radiol.2017161659
Mayo-Smith WW et al (2017) Management of incidental adrenal masses: a white paper of the ACR Incidental Findings Committee. J Am Coll Radiol 14(8):1038–1044
National Cancer Institute (NCI) (2011) The National Lung Screening Trial Research Team reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 365:395–409. https://doi.org/10.1056/NEJMoa1102873
NCCN guidelines for lung cancer screening: https://www.nccn.org/professionals/physician_gls/pdf/lung_screening.pdf
NCCN clincal practice guidelines in Oncology: Non-Small Cell Lung Cancer: https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf
Nishino M (2018) Tumor response assessment for precision cancer therapy: response evaluation criteria in solid tumors and beyond. asco.org/edbook. ASCO EDUCATIONAL BOOK
Oliver TW et al (1984) Isolated adrenal masses in nonsmall cell bronchogenic carcinoma. Radiology 153:217–218
Porte H et al (2001) Resection of adrenal metastases from non-small cell lung cancer: a multicenter study. Ann Thorac Surg 71:981–985
Purandare NC, Rangarajan V (2015) Imaging of lung cancer: implications on staging and management. Indian J Radiol Imaging 25(2):109–120. https://doi.org/10.4103/0971-3026.155831
Rusch VW, Asamura H, Watanabe H, Giroux DJ, Rami-Porta R, Goldstraw P, on Behalf of the Members of the IASLC Staging Committee (2009) The IASLC Lung Cancer Staging Project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer. J Thorac Oncol 4:568–577
Salazar AM, Westcott JL (1993) The role of transthoracic needle biopsy for the diagnosis and staging of lung cancer. Clin Chest Med 14:99–110
Sider L, Horejs D (1988) Frequency of extrathoracic metastases from bronchogenic carcinoma in patients with normal-sized hilar and mediastinal lymph nodes on CT. AJR Am J Roentgenol 151:893–895
Verschakelen JA, Bogaert J, De Wever W (2002) Computed tomography in staging for lung cancer. Eur Respir J 19(Suppl. 35):40s–48s. https://doi.org/10.1183/09031936.02.00270802
Yeh HC, Rabinowitz JG (1980) Ultrasonography and computed tomography of the liver. Radiol Clin North Am 18:321–338
Yokoi K et al (1999) Detection of brain metastasis in potentially operable non-small cell lung cancer: a comparison of CT and MRI. Chest 115:714–719
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Kukava, S., Tsivtsivadze, G. (2022). Role of Radiologic Imaging in Lung Cancer. In: Jeremić, B. (eds) Advances in Radiation Oncology in Lung Cancer. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2022_302
Download citation
DOI: https://doi.org/10.1007/174_2022_302
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-34846-4
Online ISBN: 978-3-031-34847-1
eBook Packages: MedicineMedicine (R0)