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Translocation between chromosome 7 and chromosome 22, t(7;22)(p22;q12), in a patient with chronic myelocytic leukemia

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Summary

A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in addition to the variant translocation.

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Authors and Affiliations

  1. Karolinska Institute, Department of Medicine, Section of Oncology and Hematology, Huddinge Hospital, Huddinge, Sweden

    Gösta Gahrton

  2. Institute of Medical Cell Genetics, Karolinska Institute, Stockholm, Sweden

    Gösta Gahrton, Kristina Friberg & Lore Zech

Authors
  1. Gösta Gahrton
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  2. Kristina Friberg
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  3. Lore Zech
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Gahrton, G., Friberg, K. & Zech, L. Translocation between chromosome 7 and chromosome 22, t(7;22)(p22;q12), in a patient with chronic myelocytic leukemia. Hum Genet 49, 225–227 (1979). https://doi.org/10.1007/BF00277647

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  • DOI: https://doi.org/10.1007/BF00277647

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