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Small Bowel and Appendix Cancers

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Textbook of Gastrointestinal Oncology

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Abstract

Small bowel and appendiceal malignancies are rare entities that constitute about 2% of all gastrointestinal (GI) malignancies with an incidence of approximately 8000 new cases per year in the United States. Cancers arising in these locations vary in histology, clinical presentation, treatment, and outcomes. Neuroendocrine tumors (NETs) are the most common type of small bowel tumors, accounting for approximately 44%, followed by adenocarcinoma (33%), lymphoma (15%), and sarcoma (8%). Given the low prevalence of both small bowel and appendix cancers, there is a lack of prospective randomized trials to establish clear evidence-based guidelines for treatment. Early stage tumors of the small bowel and appendix are usually treated by surgical resection. The role of adjuvant therapy is dependent on histology and stage. Adenocarcinoma of the small bowel and appendix are usually treated similar to colorectal cancer.

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Authors and Affiliations

  1. Department of Hematology and Medical Oncology, Northern Light Eastern Maine Medical Center, Lafayette Family Cancer Center, Brewer, ME, USA

    Astrid Belalcazar-Portacio

  2. Department of Hematology and Medical Oncology, Emory University, Winship Cancer Institute, Atlanta, GA, USA

    Walid L. Shaib

  3. Clinical Research, Department of Hematology and Medical Oncology, Emory University School of Medicine/Winship Cancer Institute of Emory University, Atlanta, GA, USA

    Bassel F. El-Rayes

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  1. Astrid Belalcazar-Portacio
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  2. Walid L. Shaib
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  3. Bassel F. El-Rayes
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Correspondence to Bassel F. El-Rayes .

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Editors and Affiliations

  1. Department of Medical Oncology, Hacettepe University Institute of Cancer, Sihhiye, Ankara, Turkey

    Suayib Yalcin

  2. Department of Oncology, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA

    Philip A. Philip

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Belalcazar-Portacio, A., Shaib, W.L., El-Rayes, B.F. (2019). Small Bowel and Appendix Cancers. In: Yalcin, S., Philip, P. (eds) Textbook of Gastrointestinal Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-18890-0_6

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