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Pharmacologic Treatment of Pediatric Hypertension

Pediatric Hypertension

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Abstract

Hypertension has traditionally been regarded as a rare occurrence in childhood and adolescence; however, there is compelling evidence to suggest that elevated blood pressure is increasingly common in this population, particularly in those with obesity. As a result, pediatricians increasingly are expected to evaluate and manage patients with elevated blood pressure. An increased emphasis on conducting drug trials in children over the last two decades has yielded important advances with respect to evidence-based data regarding the safety and efficacy of antihypertensive medications in children and adolescents. Despite these advances, data to definitively guide selection of first-line antihypertensive agents is lacking. This chapter provides an overview of antihypertensive drug therapy in children, including indications for treatment. A detailed review of available antihypertensive agents is provided with an emphasis on pediatric specific data with respect to dosing, safety, and efficacy. In addition, a rational approach to selecting an appropriate medication with respect to pathophysiology, putative benefit, and likelihood for side effects is reviewed.

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  1. Division of Nephrology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, 02115, USA

    Michael A. Ferguson

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  1. Division of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA

    Joseph Flynn

  2. Massachusetts General Hospital, Boston, Massachusetts, USA

    Julie R. Ingelfinger

  3. Arkansas Children's Hospital, University of Arkansas Medical Science, Little Rock, Arkansas, USA

    Karen Redwine

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  1. Department of Pediatrics, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, 1 Children's Way, 72202, Little Rock, AR, USA

    Karen M. Redwine MD

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Ferguson, M.A. (2017). Pharmacologic Treatment of Pediatric Hypertension. In: Flynn, J., Ingelfinger, J., Redwine, K. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-31420-4_36-1

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  1. Latest

    Pharmacologic Treatment of Pediatric Hypertension
    Published:
    28 July 2022

    DOI: https://doi.org/10.1007/978-3-319-31420-4_36-2

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    Pharmacologic Treatment of Pediatric Hypertension
    Published:
    08 May 2017

    DOI: https://doi.org/10.1007/978-3-319-31420-4_36-1

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