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Genomic Applications in Pharmacogenomics

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Genomic Applications in Pathology

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Abstract

Pharmacogenomics is the study of the influence of the effect of genetic variations between individuals on drug efficacy, metabolism, and toxicity. With advances in pharmacogenomics, physicians will be able to prescribe the right drug and at the correct dose based on the genomic profile of their patients, thus maximizing the efficacy while minimizing adverse effects. Genomic principles guide the design, implementation, analysis, and inference from pharmacogenomic studies. Applications of genomic principles in pharmacogenomics hold promise for personalized medicine, novel drug discovery and development, and deeper insights into the biological mechanisms.

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Authors and Affiliations

  1. Division of General Internal, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Rehan Qayyum

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  1. Departments of Pathology, Oncology and Urology, Johns Hopkins University, Baltimore, Maryland, USA

    George Jabboure Netto

  2. Department of Pathology, Stanford University School of Medicine, Stanford, California, USA

    Iris Schrijver

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Qayyum, R. (2015). Genomic Applications in Pharmacogenomics. In: Netto, G., Schrijver, I. (eds) Genomic Applications in Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0727-4_31

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