| 1 | Enzymatic assembly of DNA molecules up to several hundred kilobases | 2009 | 7,498 |
| 2 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues | 1969 | 5,211 |
| 3 | Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme | 1976 | 3,539 |
| 4 | Photosynthesis under drought and salt stress: regulation mechanisms from whole plant to cell. | 2009 | 3,068 |
| 5 | Regulation Mechanisms and Signaling Pathways of Autophagy | 2009 | 2,813 |
| 6 | Enzymatic Basis for Active Transport of Na+ and K+ Across Cell Membrane | 1965 | 1,617 |
| 7 | Enzymic determination of d(−)-β-hydroxybutyric acid and acetoacetic acid in blood | 1962 | 1,235 |
| 8 | ENZYMATIC PROPERTIES OF THE INNER AND OUTER MEMBRANES OF RAT LIVER MITOCHONDRIA | 1968 | 1,203 |
| 9 | An enzymic method for the trace iodination of immunoglobulins and other proteins | 1969 | 1,141 |
| 10 | Preparation of rat liver cells | 1973 | 1,050 |
| 11 | Enzymatic iodination of polypeptides with I to high specific activity | 1971 | 968 |
| 12 | A Linear Steady-State Treatment of Enzymatic Chains | 1974 | 897 |
| 13 | Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect | 1971 | 847 |
| 14 | Enzymatic Defect in Fabry's Disease — Ceramidetrihexosidase Deficiency | 1967 | 813 |
| 15 | A Note on the Kinetics of Enzyme Action | 1925 | 806 |
| 16 | Solubilization and Purification of Enzymatically Active Glutathione -Transferase (pGEX) Fusion Proteins | 1993 | 805 |
| 17 | Spectrophotometric measurements of the enzymatic formation of fumaric and -aconitic acids | 1950 | 762 |
| 18 | Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex | 2003 | 752 |
| 19 | THE SUBMITOCHONDRIAL LOCALIZATION OF MONOAMINE OXIDASE : An Enzymatic Marker for the Outer Membrane of Rat Liver Mitochondria | 1967 | 730 |
| 20 | Mechanisms of enzymatic glycoside hydrolysis | 1994 | 726 |
| 21 | Form and functionality of starch | 2009 | 719 |
| 22 | Top bar navigation | 2018 | 715 |
| 23 | Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine. | 1993 | 711 |
| 24 | Biotechnological approach of improving plant salt tolerance using antioxidants as markers | 2009 | 707 |
| 25 | Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis | 2009 | 706 |
| 26 | Substructure of the myosin molecule | 1969 | 691 |
| 27 | Evaluation of Pollen Viability by Enzymatically Induced Fluorescence; Intracellular Hydrolysis of Fluorescein Diacetate | 1970 | 674 |
| 28 | Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA | 1993 | 657 |
| 29 | Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals | 2009 | 644 |
| 30 | Oscillatory behavior in enzymatic control processes | 1965 | 628 |
| 31 | AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES : I. CHICK EMBRYO FIBROBLAST CULTURES TRANSFORMED BY AVIAN RNA TUMOR VIRUSES | 1973 | 618 |
| 32 | Carbon Nanozymes: Enzymatic Properties, Catalytic Mechanism, and Applications | 2018 | 607 |
| 33 | Metabolism of glucocerebrosides II. Evidence of an enzymatic deficiency in Gaucher's disease | 1965 | 603 |
| 34 | THE ENZYMATIC IODINATION OF THE RED CELL MEMBRANE | 1972 | 593 |
| 35 | Two-Metal Ion Catalysis in Enzymatic Acyl- and Phosphoryl-Transfer Reactions | 1996 | 555 |
| 36 | Metabolic Differentiation of Distinct Muscle Types at the Level of Enzymatic Organization | 1969 | 537 |
| 37 | Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes | 1993 | 518 |
| 38 | A review of the current state of biodiesel production using enzymatic transesterification | 2009 | 513 |
| 39 | An improved method for enzymic determination of glucose in the presence of maltose | 1969 | 501 |
| 40 | The enzymic hydrolysis of adenosine triphosphate by liver mitochondria. 1. Activities at different pH values | 1957 | 495 |
| 41 | On the Enzymology of Amino Acid Transport: Transport in kidney and probably other tissues is mediated by a cycle of enzymic reactions involving glutathione. | 1973 | 493 |
| 42 | Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification-A role in pathogenesis and antiproliferative chemotherapy | 1996 | 491 |
| 43 | Enzymatic Polymer Synthesis: An Opportunity for Green Polymer Chemistry | 2009 | 485 |
| 44 | Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. | 1996 | 472 |
| 45 | Determination of inorganic sulphate in studies on the enzymic and non-enzymic hydrolysis of carbohydrate and other sulphate esters | 1961 | 466 |
| 46 | Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin | 2009 | 451 |
| 47 | Mitigating release of the potent greenhouse gas N2O from the nitrogen cycle – could enzymic regulation hold the key? | 2009 | 447 |
| 48 | Isolation, cultivation, and characterization of human mesenchymal stem cells | 2018 | 444 |
| 49 | Endogenous non-enzymatic antioxidants in the human body | 2018 | 425 |
| 50 | Culture of enzymatically dispersed pituitary cells: functional validation of a method. | 1972 | 422 |
| 51 | Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons | 1997 | 421 |
| 52 | Acceleration of phenyl ester cleavage by cycloamyloses. A model for enzymic specificity | 1967 | 402 |
| 53 | Rapid Enzymatic Measurement of Blood Lactate and Pyruvate | 1967 | 397 |
| 54 | Preparation of rat liver cells | 1972 | 397 |
| 55 | Metabolism of amino-acids: IV. The synthesis of glutamine from glutamic acid and ammonia, and the enzymic hydrolysis of glutamine in animal tissues | 1935 | 394 |
| 56 | α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling | 2018 | 394 |
| 57 | Negative cooperativity in enzyme action. Binding of diphosphopyridine nucleotide to glyceraldehyde-3-phosphate dehydrogenase | 1968 | 389 |
| 58 | Enzymatic iron and uranium reduction by sulfate-reducing bacteria | 1993 | 389 |
| 59 | Enzymatic asymmetric synthesis of chiral amino acids | 2018 | 389 |
| 60 | Complete assignment of cytochrome c resonance Raman spectra via enzymic reconstitution with isotopically labeled hemes | 1993 | 386 |
| 61 | Hydroxylation-Induced Migration: The NIH Shift: Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. | 1967 | 374 |
| 62 | Enzymic iodination. A probe for accessible surface proteins of normal and neoplastic lymphocytes | 1971 | 370 |
| 63 | An enzymatic fluorometric micromethod for the determination of glycerol | 1966 | 367 |
| 64 | Polylactide stereochemistry: effect on enzymic degradability | 1994 | 367 |
| 65 | Co-operative non-enzymatic base recognition III. Kinetics of the helix—coil transition of the oligoribouridylic · oligoriboadenylic acid system and of oligoriboadenylic acid alone at acidic pH | 1971 | 363 |
| 66 | Injectable chitosan-based hydrogels for cartilage tissue engineering | 2009 | 362 |
| 67 | Enzyme Mechanisms for Polycyclic Triterpene Formation | 2000 | 352 |
| 68 | Enzymic and non-enzymic antioxidants in epidermis and dermis of human skin. | 1994 | 350 |
| 69 | Steady-state analysis of kinetic isotope effects in enzymic reactions | 1975 | 345 |
| 70 | Enzymatic biodiesel synthesis – Key factors affecting efficiency of the process | 2009 | 340 |
| 71 | Fluorometric determination of aspartate, glutamate, and γ-aminobutyrate in nerve tissue using enzymic method | 1966 | 338 |
| 72 | N-CAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid | 1994 | 336 |
| 73 | Enzymatic radioiodination of gonadotropins. | 1972 | 335 |
| 74 | Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope | 1997 | 335 |
| 75 | Enzymatic Metabolism of Drugs and other Foreign Compounds | 1958 | 334 |
| 76 | Naturally Occurring Human Glutathione S-transferase GSTP1-1 Isoforms with Isoleucine and Valine in Position 104 Differ in Enzymic Properties | 1994 | 334 |
| 77 | Enzymatic and Metabolic Adaptations in Animals | 1956 | 333 |
| 78 | Enzymic analysis of microbial pattern and process | 1994 | 330 |
| 79 | Oxidative degradation of aromatic hydrocarbons by microorganisms. I. Enzymic formation of catechol from benzene | 1968 | 327 |
| 80 | Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide | 1995 | 324 |
| 81 | Determination of Total, Soluble, and Insoluble Dietary Fiber in Foods—Enzymatic-Gravimetric Method, MES-TRIS Buffer: Collaborative Study | 1992 | 322 |
| 82 | Assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymic radioisotopic displacement | 1968 | 318 |
| 83 | Convergent evolution of similar enzymatic function on different protein folds: The hexokinase, ribokinase, and galactokinase families of sugar kinases | 1993 | 318 |
| 84 | Selective aerobic oxidation reactions using a combination of photocatalytic water oxidation and enzymatic oxyfunctionalizations | 2017 | 318 |
| 85 | Externally disposed plasma membrane proteins. I. Enzymatic iodination of mouse L cells. | 1975 | 312 |
| 86 | Understanding enzymic catalysis: the importance of short, strong hydrogen bonds. | 1997 | 310 |
| 87 | Quality of Fish Protein Hydrolysates from Herring (Clupea harengus) | 1994 | 309 |
| 88 | Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis | 1995 | 308 |
| 89 | Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and HO detection | 2018 | 306 |
| 90 | Determination of Glucose by an Improved Enzymatic Procedure | 1961 | 305 |
| 91 | ENZYMATIC METHYLATION OF ARSENIC SPECIES AND OTHER NEW APPROACHES TO ARSENIC TOXICITY | 1997 | 305 |
| 92 | Climbing Nitrogenase: Toward a Mechanism of Enzymatic Nitrogen Fixation | 2009 | 301 |
| 93 | Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions | 1958 | 299 |
| 94 | An injectable, enzymatically gellable, gelatin derivative for drug delivery and tissue engineering | 2009 | 299 |
| 95 | O2 Reduction in Enzymatic Biofuel Cells | 2018 | 299 |
| 96 | SOD and catalase inactivation by singlet oxygen and peroxyl radicals | 1996 | 298 |
| 97 | The amino-acid sequence in the phenylalanyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates | 1951 | 297 |
| 98 | The enzymatic formation of prostaglandin E from arachidonic acid prostaglandins and related factors 32 | 1964 | 292 |
| 99 | Enantioselective synthesis through enzymatic asymmetrization | 1996 | 291 |
| 100 | An enzymic reduction system for metmyoglobin and methemoglobin, and its application to functional studies of oxygen carriers | 1973 | 289 |
