Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer | Nature Genetics | 1999 | 1.6K |
c-Myc target genes involved in cell growth, apoptosis, and metabolism | Molecular and Cellular Biology | 1999 | 1.3K |
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage | Nature | 1999 | 804 |
Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery | Genes and Development | 1999 | 361 |
Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease | Journal of Biological Chemistry | 1999 | 272 |
Cloning and characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1 | Journal of Neuroscience | 1999 | 242 |
Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression | Cell | 1999 | 231 |
p15INK4BCpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing | Blood | 1999 | 198 |
A mutation in NRL is associated with autosomal dominant retinitis pigmentosa | Nature Genetics | 1999 | 180 |
Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair | Immunity | 1999 | 104 |
Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle | Journal of Cell Biology | 1999 | 99 |
NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae | Molecular and Cellular Biology | 1999 | 89 |
RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex | Molecular and Cellular Biology | 1999 | 86 |
The conserved core of a human SIR2 homologue functions in yeast silencing | Molecular Biology of the Cell | 1999 | 83 |
Expression of the optx2 homeobox gene during mouse development | Mechanisms of Development | 1999 | 55 |
Yeast carboxyl-terminal domain kinase I positively and negatively regulates RNA polymerase II carboxyl-terminal domain phosphorylation | Journal of Biological Chemistry | 1999 | 53 |
Detecting patterns of protein distribution and gene expression in silico | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 50 |
Identification of Haemophilus influenzae Rd transformation genes using cassette mutagenesis | Microbiology (United Kingdom) | 1999 | 47 |
Human and nematode orthologs--lessons from the analysis of 1800 human genes and the proteome of Caenorhabditis elegans | Gene | 1999 | 42 |
Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line | Journal of Biological Chemistry | 1999 | 38 |
Growth retardation and neonatal lethality in mice with a homozygous deletion in the C-terminal domain of RNA polymerase II | Molecular Genetics and Genomics | 1999 | 36 |
Lack of linkage or association between schizophrenia and the polymorphic trinucleotide repeat within the KCNN3 gene on chromosome 1q21 | | 1999 | 28 |
Presence of GH-dependent IGF-II mRNA in the diffuse pancreatic tissue of a teleost | Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology | 1999 | 23 |
Sequence and location of SIX3, a homeobox gene expressed in the human eye | Ophthalmic Genetics | 1999 | 16 |
Serum sCD23 level in patients with AIDS-related non-Hodgkin's lymphoma is associated with absence of Epstein-Barr virus in tumor tissue | Clinical Immunology | 1999 | 11 |