| Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer | Nature Genetics | 1999 | 1.6K |
| Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases | Cancer Research | 1999 | 1.6K |
| c-Myc target genes involved in cell growth, apoptosis, and metabolism | Molecular and Cellular Biology | 1999 | 1.3K |
| Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia | Cancer Research | 1999 | 859 |
| 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage | Nature | 1999 | 804 |
| Identification and classification of p53-regulated genes | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 386 |
| CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 265 |
| Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers | Cancer Research | 1999 | 254 |
| High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations | Journal of Virology | 1999 | 206 |
| p15INK4BCpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing | Blood | 1999 | 198 |
| The biology of hormone refractory prostate cancer. Why does it develop? | Urologic Clinics of North America | 1999 | 196 |
| Triggering the interferon response: the role of IRF-3 transcription factor | Journal of Interferon and Cytokine Research | 1999 | 187 |
| Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300 | Journal of Virology | 1999 | 173 |
| Gene transfer by DNA-gelatin nanospheres | Archives of Biochemistry and Biophysics | 1999 | 160 |
| Methylation and silencing of the Thrombospondin-1 promoter in human cancer | Oncogene | 1999 | 142 |
| Cancer vaccines | Journal of Clinical Oncology | 1999 | 123 |
| Leukemogenesis by CBF oncoproteins | Leukemia | 1999 | 90 |
| KSHV strains: the origins and global spread of the virus | Seminars in Cancer Biology | 1999 | 85 |
| Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro | Magnetic Resonance in Medicine | 1999 | 84 |
| Cancer risk in collagenous colitis | Inflammatory Bowel Diseases | 1999 | 73 |
| Expression of Epstein-Barr Virus BamHI-A Rightward Transcripts in Latently Infected B Cells From Peripheral Blood | Blood | 1999 | 70 |
| Thapsigargin analogues for targeting programmed death of androgen-independent prostate cancer cells | Bioorganic and Medicinal Chemistry | 1999 | 59 |
| p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing | Blood | 1999 | 59 |
| Diagnosis of renal cancer by molecular urinalysis | Journal of the National Cancer Institute | 1999 | 57 |
| The Epstein-Barr virus latency BamHI-Q promoter is positively regulated by STATs and Zta interference with JAK/STAT activation leads to loss of BamHI-Q promoter activity | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 57 |
