| Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer | Nature Genetics | 1999 | 1.6K |
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Annual Review of Cell and Developmental Biology | 1999 | 1.6K |
| c-Myc target genes involved in cell growth, apoptosis, and metabolism | Molecular and Cellular Biology | 1999 | 1.3K |
| 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage | Nature | 1999 | 804 |
| Cellular and molecular biology of the aquaporin water channels | Annual Review of Biochemistry | 1999 | 684 |
| Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha | Journal of Clinical Investigation | 1999 | 517 |
| The Arabidopsis thaliana proton transporters, AtNhx1 and Avp1, can function in cation detoxification in yeast | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 500 |
| Haem oxygenase-1 prevents cell death by regulating cellular iron | Nature Cell Biology | 1999 | 448 |
| Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2 | Cancer Research | 1999 | 421 |
| Identification and classification of p53-regulated genes | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 386 |
| Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies | Circulation Research | 1999 | 382 |
| Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain | European Journal of Neuroscience | 1999 | 330 |
| Perspectives on oxygen sensing | Cell | 1999 | 323 |
| An autosomal genomic screen for autism | American Journal of Medical Genetics Part A | 1999 | 304 |
| Function of the c-Myc oncogenic transcription factor | Experimental Cell Research | 1999 | 297 |
| Food transport and bolus formation during complete feeding sequences on foods of different initial consistency | Dysphagia | 1999 | 291 |
| Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation | Cell | 1999 | 290 |
| Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers | Cancer Research | 1999 | 254 |
| Cloning and characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1 | Journal of Neuroscience | 1999 | 242 |
| An antiviral mechanism of nitric oxide: inhibition of a viral protease | Immunity | 1999 | 200 |
| p15INK4BCpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing | Blood | 1999 | 198 |
| De novo alu-element insertions in FGFR2 identify a distinct pathological basis for Apert syndrome | American Journal of Human Genetics | 1999 | 198 |
| Diffusion magnetic resonance imaging: its principle and applications | The Anatomical Record | 1999 | 197 |
| Familial dwarfism due to a novel mutation of the growth hormone-releasing hormone receptor gene | Journal of Clinical Endocrinology and Metabolism | 1999 | 171 |
| Nuclear targeting of mutant Huntingtin increases toxicity | Molecular and Cellular Neurosciences | 1999 | 166 |
