| # | Title | Journal | Year | Citations |
|---|
|
| 1 | HES and HERP families: Multiple effectors of the notch signaling pathway | Journal of Cellular Physiology | 2003 | 1,112 |
| 2 | The Quest for Human Cancer Viruses: A new approach to an old problem reveals cancer induction in hamsters by human adenovirus | Science | 1962 | 562 |
| 3 | It Takes Two to Tango: When and Where Dual Nutrient (N & P) Reductions Are Needed to Protect Lakes and Downstream Ecosystems | Environmental Science & Technology | 2016 | 522 |
| 4 | DETERMINATION OF SELECT ANTIDEPRESSANTS IN FISH FROM AN EFFLUENT-DOMINATED STREAM | Environmental Toxicology and Chemistry | 2005 | 493 |
| 5 | A new method for detecting and interpreting biodiversity and ecological community thresholds | Methods in Ecology and Evolution | 2010 | 412 |
| 6 | Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames | Nucleic Acids Research | 1994 | 333 |
| 7 | HEMOPOIETIC COLONY STUDIES | Journal of Experimental Medicine | 1968 | 324 |
| 8 | Age‐related changes in the gut microbiota influence systemic inflammation and stroke outcome | Annals of Neurology | 2018 | 316 |
| 9 | Proprioceptor Pathway Development Is Dependent on MATH1 | Neuron | 2001 | 284 |
| 10 | Disproportionate impact of the COVID-19 pandemic on immigrant communities in the United States | PLoS Neglected Tropical Diseases | 2020 | 274 |
| 11 | Regulation of Cytochrome P450 Aromatase Messenger Ribonucleic Acid and Activity by Steroids and Gonadotropins in Rat Granulosa Cells* | Endocrinology | 1991 | 223 |
| 12 | Insulin signaling and the regulation of insect diapause | Frontiers in Physiology | 2013 | 215 |
| 13 | Diversification and biogeography of Juniperus (Cupressaceae): variable diversification rates and multiple intercontinental dispersals | New Phytologist | 2010 | 214 |
| 14 | Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 211 |
| 15 | Gene Pathways Associated With Prognosis and Chemotherapy Sensitivity in Molecular Subtypes of Breast Cancer | Journal of the National Cancer Institute | 2011 | 209 |
| 16 | Prophage-mediated defence against viral attack and viral counter-defence | Nature Microbiology | 2017 | 209 |
| 17 | Implications of GABAergic Neurotransmission in Alzheimer’s Disease | Frontiers in Aging Neuroscience | 2016 | 205 |
| 18 | How Many Mountains Can We Mine? Assessing the Regional Degradation of Central Appalachian Rivers by Surface Coal Mining | Environmental Science & Technology | 2012 | 201 |
| 19 | Climate, pCO2 and terrestrial carbon cycle linkages during late Palaeozoic glacial–interglacial cycles | Nature Geoscience | 2016 | 201 |
| 20 | Adaptive introgression enables evolutionary rescue from extreme environmental pollution | Science | 2019 | 195 |
| 21 | Periostin Is Essential for the Integrity and Function of the Periodontal Ligament During Occlusal Loading in Mice | Journal of Periodontology | 2008 | 194 |
| 22 | High Mitochondrial Respiration and Glycolytic Capacity Represent a Metabolic Phenotype of Human Tolerogenic Dendritic Cells | Journal of Immunology | 2015 | 192 |
| 23 | The global burden of disease study 2013: What does it mean for the NTDs? | PLoS Neglected Tropical Diseases | 2017 | 191 |
| 24 | Towards personalized treatment for early stage HER2-positive breast cancer | Nature Reviews Clinical Oncology | 2020 | 189 |
| 25 | Comparison of the whey acidic protein genra of the rat and mouse | Nucleic Acids Research | 1984 | 180 |
| 26 | Status of vaccine research and development of vaccines for leishmaniasis | Vaccine | 2016 | 180 |
| 27 | Formation of an IKKα-Dependent Transcription Complex Is Required for Estrogen Receptor-Mediated Gene Activation | Molecular Cell | 2005 | 177 |
| 28 | Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 “Don't Eat Me” Signals | Clinical Cancer Research | 2015 | 174 |
| 29 | Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States | JAMA Pediatrics | 2017 | 168 |
| 30 | Absence of the Complement Anaphylatoxin C3a Receptor Suppresses Th2 Effector Functions in a Murine Model of Pulmonary Allergy | Journal of Immunology | 2002 | 165 |
| 31 | Thresholds, breakpoints, and nonlinearity in freshwaters as related to management | Journal of the North American Benthological Society | 2010 | 162 |
| 32 | HEMOPOIEITC SPLEEN COLONY STUDIES | Journal of Experimental Medicine | 1967 | 159 |
| 33 | COVID-19 vaccine design: the Janus face of immune enhancement | Nature Reviews Immunology | 2020 | 159 |
| 34 | A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicularfeminized mouse | Nucleic Acids Research | 1991 | 154 |
| 35 | The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties | PLoS Medicine | 2018 | 153 |
| 36 | A Role for Plk1 Phosphorylation of NudC in Cytokinesis | Developmental Cell | 2003 | 149 |
| 37 | Transcriptional Regulation by Steroid Receptor Coactivator Phosphorylation | Endocrine Reviews | 2005 | 147 |
| 38 | Structure of a Biologically Active Estrogen Receptor-Coactivator Complex on DNA | Molecular Cell | 2015 | 147 |
| 39 | Probabilistic ecological hazard assessment of parabens using Daphnia magna and Pimephales promelas | Environmental Toxicology and Chemistry | 2009 | 145 |
| 40 | Patch Isolation, Corridor Effects, and Colonization by a Resident Sparrow in a Managed Pine Woodland | Conservation Biology | 1995 | 142 |
| 41 | How novel is too novel? Stream community thresholds at exceptionally low levels of catchment urbanization | Ecological Applications | 2011 | 141 |
| 42 | CD11c/CD18 Expression Is Upregulated on Blood Monocytes During Hypertriglyceridemia and Enhances Adhesion to Vascular Cell Adhesion Molecule-1 | Arteriosclerosis, Thrombosis, and Vascular Biology | 2011 | 140 |
| 43 | Serum Steroid Levels During the Menstrual Cycle in a Bilaterally Adrenalectomized Woman | Journal of Clinical Endocrinology and Metabolism | 1973 | 138 |
| 44 | A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now | Lancet Infectious Diseases, The | 2017 | 137 |
| 45 | Palaearctic biogeography revisited: evidence for the existence of a North African refugium for Western Palaearctic biota | Journal of Biogeography | 2014 | 136 |
| 46 | Identification of FOXO targets that generate diverse features of the diapause phenotype in the mosquito Culex pipiens | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 133 |
| 47 | First detection of Anopheles stephensi Liston, 1901 (Diptera: culicidae) in Ethiopia using molecular and morphological approaches | Acta Tropica | 2018 | 128 |
| 48 | Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice | Nucleic Acids Research | 1987 | 125 |
| 49 | ENANTIOSPECIFIC TOXICITY OF THE β-BLOCKER PROPRANOLOL TO DAPHNIA MAGNA AND PIMEPHALES PROMELAS | Environmental Toxicology and Chemistry | 2006 | 125 |
| 50 | Seroprevalence estimates for toxocariasis in people worldwide: A systematic review and meta-analysis | PLoS Neglected Tropical Diseases | 2019 | 124 |
