Tracking cancer drugs in living cells by thermal profiling of the proteome | Science | 2014 | 526 |
The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity | Nature Structural and Molecular Biology | 2014 | 250 |
Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity | Nature Communications | 2014 | 227 |
Eukaryotic V-ATPase: novel structural findings and functional insights | Biochimica Et Biophysica Acta - Bioenergetics | 2014 | 118 |
Improving microbial biogasoline production in Escherichia coli using tolerance engineering | MBio | 2014 | 91 |
Klf2 is an essential factor that sustains ground state pluripotency | Cell Stem Cell | 2014 | 90 |
Microbial tolerance engineering toward biochemical production: from lignocellulose to products | Current Opinion in Biotechnology | 2014 | 70 |
Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility | Biotechnology and Bioengineering | 2014 | 65 |
Sox2: masterminding the root of cancer | Cancer Cell | 2014 | 45 |
Peptide-perylene diimide functionalized magnetic nano-platforms for fluorescence turn-on detection and clearance of bacterial lipopolysaccharides | Chemical Communications | 2014 | 41 |
Native chemical ubiquitination using a genetically incorporated azidonorleucine | Chemical Communications | 2014 | 36 |
Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure | Stem Cells | 2014 | 35 |
Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases | Structure | 2014 | 35 |
Cryo-electron microscopic structure of SecA protein bound to the 70S ribosome | Journal of Biological Chemistry | 2014 | 33 |
Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle | Molecular Endocrinology | 2014 | 32 |
Coupled reductive and oxidative sulfur cycling in the phototrophic plate of a meromictic lake | Geobiology | 2014 | 28 |
Pancreatic cancer gene therapy using an siRNA-functionalized single walled carbon nanotubes (SWNTs) nanoplex | Biomaterials Science | 2014 | 27 |
RIF1: a novel regulatory factor for DNA replication and DNA damage response signaling | DNA Repair | 2014 | 22 |
Cysteine deleted protegrin-1 (CDP-1): anti-bacterial activity, outer-membrane disruption and selectivity | Biochimica Et Biophysica Acta - General Subjects | 2014 | 21 |
Molecular dynamics simulations demonstrate the regulation of DNA-DNA attraction by H4 histone tail acetylations and mutations | Biopolymers | 2014 | 20 |
A conserved mechanism for binding of p53 DNA-binding domain and anti-apoptotic Bcl-2 family proteins | Molecules and Cells | 2014 | 19 |
Nitrile reductase as a biocatalyst: opportunities and challenges | Catalysis Science and Technology | 2014 | 18 |
The role of SON in splicing, development, and disease | Wiley Interdisciplinary Reviews RNA | 2014 | 18 |
Soluble expression and partial purification of recombinant human erythropoietin from E. coli | Protein Expression and Purification | 2014 | 17 |
Principles of electrostatic interactions and self-assembly in lipid/peptide/DNA systems: applications to gene delivery | Advances in Colloid and Interface Science | 2014 | 15 |