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exaly
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Nanyang Technological University
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Department of Medical Biochemistry and Biophysics
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Top Articles
Department of Medical Biochemistry and Biophysics
Nanyang Technological University
27
Articles
2.1K
Citations
8.3
avg. Impact Factor
13
h-index
Most Cited Articles of Department of Medical Biochemistry and Biophysics
Title
Journal
Year
Citations
Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay
Science
2013
982
Tracking cancer drugs in living cells by thermal profiling of the proteome
Science
2014
526
Understanding transport by the major facilitator superfamily (MFS): structures pave the way
Nature Reviews Molecular Cell Biology
2016
214
The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies
Annual Review of Pharmacology and Toxicology
2016
156
Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell
Nature Communications
2013
63
Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
Structure
2014
35
Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide
Biophysical Journal
2016
17
Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1
PLoS ONE
2012
17
The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor
Nucleic Acids Research
2013
16
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate
PLoS ONE
2015
15
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism
PLoS ONE
2012
15
Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase
Journal of Lipid Research
2013
15
Nanobody mediated crystallization of an archeal mechanosensitive channel
PLoS ONE
2013
15
Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31
PLoS ONE
2013
15
Structure of the C-Terminal Domain of the Multifunctional ICP27 Protein from Herpes Simplex Virus 1
Journal of Virology
2015
13
Digital health professions education on chronic wound management: A systematic review
International Journal of Nursing Studies
2020
12
Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A
PLoS ONE
2014
11
Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein
Virology
2015
10
Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy
Nature Communications
2021
10
Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine
PLoS ONE
2015
9
High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA
FASEB Journal
2012
9
The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity
FEBS Journal
2016
8
Interaction, uptake, and processing of LbL-coated microcarriers by PMNs
Cytometry Part A: the Journal of the International Society for Analytical Cytology
2011
7
Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates
PLoS ONE
2013
3
A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane.
Proceedings of the National Academy of Sciences of the United States of America
2022
2
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