Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD | Gut | 2016 | 327 |
Five-Year Clinical Trial on Atropine for the Treatment of Myopia 2: Myopia Control with Atropine 0.01% Eyedrops | Ophthalmology | 2016 | 270 |
Effectiveness of activity trackers with and without incentives to increase physical activity (TRIPPA): a randomised controlled trial | Lancet Diabetes and Endocrinology,the | 2016 | 259 |
Cell refractive index for cell biology and disease diagnosis: past, present and future | Lab on A Chip | 2016 | 243 |
Understanding transport by the major facilitator superfamily (MFS): structures pave the way | Nature Reviews Molecular Cell Biology | 2016 | 214 |
Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review | Systematic Reviews | 2016 | 168 |
The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies | Annual Review of Pharmacology and Toxicology | 2016 | 156 |
Recent advances of semiconducting polymer nanoparticles in in vivo molecular imaging | Journal of Controlled Release | 2016 | 154 |
A mussel-inspired double-crosslinked tissue adhesive intended for internal medical use | Acta Biomaterialia | 2016 | 150 |
Hedgehog signalling | Development (Cambridge) | 2016 | 141 |
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells | Rna | 2016 | 132 |
Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for bone tissue engineering | Biomaterials | 2016 | 131 |
High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 124 |
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage | Nature Communications | 2016 | 123 |
Crystal structure of unlinked NS2B-NS3 protease from Zika virus | Science | 2016 | 110 |
Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides | Journal of Colloid and Interface Science | 2016 | 109 |
Climate Change and Aedes Vectors: 21st Century Projections for Dengue Transmission in Europe | EBioMedicine | 2016 | 100 |
The importance of understanding individual differences in Down syndrome | F1000Research | 2016 | 98 |
Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development | International Journal of Obstetric Anesthesia | 2016 | 95 |
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types | Nature Communications | 2016 | 95 |
Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells | Cell Reports | 2016 | 90 |
Monocyte cell membrane-derived nanoghosts for targeted cancer therapy | Nanoscale | 2016 | 85 |
Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae | PLoS ONE | 2016 | 80 |
A State-of-the-Science Overview of Randomized Controlled Trials Evaluating Acute Management of Moderate-to-Severe Traumatic Brain Injury | Journal of Neurotrauma | 2016 | 74 |
Assessing Seasonal Risks for the Introduction and Mosquito-borne Spread of Zika Virus in Europe | EBioMedicine | 2016 | 73 |