Phosphatidylinositol-3-OH kinases are Rab5 effectors | Nature Cell Biology | 1999 | 503 |
Rab5 regulates motility of early endosomes on microtubules | Nature Cell Biology | 1999 | 382 |
Caveolin-3 associates with developing T-tubules during muscle differentiation | Journal of Cell Biology | 1997 | 290 |
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia | Science | 2016 | 185 |
A phosphotyrosine interaction domain | Cell | 1995 | 185 |
GABAergic and glutamatergic efferents of the mouse ventral tegmental area | Journal of Comparative Neurology | 2014 | 128 |
IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins | Cell Metabolism | 2015 | 86 |
Pain hypersensitivity mechanisms at a glance | DMM Disease Models and Mechanisms | 2013 | 84 |
Sporadic autonomic dysregulation and death associated with excessive serotonin autoinhibition | Science | 2008 | 77 |
Noncoding RNAs: key molecules in understanding and treating pain | Trends in Molecular Medicine | 2014 | 74 |
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity | PLoS Biology | 2012 | 71 |
Trifunctional lipid probes for comprehensive studies of single lipid species in living cells | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 67 |
2-D structure of the Neurospora crassa plasma membrane ATPase as determined by electron cryomicroscopy. | EMBO Journal | 1995 | 50 |
Genome-wide identification and functional analyses of microRNA signatures associated with cancer pain | EMBO Molecular Medicine | 2013 | 42 |
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats | Analytical Chemistry | 2016 | 37 |
Novel lipid tools and probes for biological investigations | Current Opinion in Cell Biology | 2018 | 34 |
A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity | Cell Chemical Biology | 2018 | 34 |
Structure-guided examination of the mechanogating mechanism of PIEZO2 | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 30 |
Endogenous Fatty Acids Are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion | Diabetes | 2018 | 29 |
Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation | Nucleic Acids Research | 2013 | 25 |
Isoprenylation of the G protein gamma subunit is both necessary and sufficient for beta gamma dimer-mediated stimulation of phospholipase C | Biochemistry | 1996 | 24 |
Photolysis of cell-permeant caged inositol pyrophosphates controls oscillations of cytosolic calcium in a β-cell line | Chemical Science | 2019 | 14 |
High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells | Cell Chemical Biology | 2016 | 14 |
Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry | ACS Central Science | 2019 | 10 |
A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation | Biochemistry | 2018 | 8 |