| Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial | Circulation | 2004 | 667 |
| Cost-effectiveness acceptability curves--facts, fallacies and frequently asked questions | Health Economics (United Kingdom) | 2004 | 634 |
| Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group | BMC Health Services Research | 2004 | 631 |
| Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS) | Journal of Clinical Oncology | 2004 | 554 |
| Muscle weakness and falls in older adults: a systematic review and meta-analysis | Journal of the American Geriatrics Society | 2004 | 553 |
| Radiation-induced bystander effects--implications for cancer | Nature Reviews Cancer | 2004 | 377 |
| Visceral hyperalgesia and intestinal dysmotility in a mouse model of postinfective gut dysfunction | Gastroenterology | 2004 | 376 |
| Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer | Journal of Clinical Endocrinology and Metabolism | 2004 | 328 |
| Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling | American Journal of Respiratory and Critical Care Medicine | 2004 | 319 |
| Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis | Journal of Immunology | 2004 | 313 |
| Effect of a decision aid on knowledge and treatment decision making for breast cancer surgery: a randomized trial | JAMA - Journal of the American Medical Association | 2004 | 312 |
| Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36 | FASEB Journal | 2004 | 311 |
| History, challenges and perspectives of cell microencapsulation | Trends in Biotechnology | 2004 | 294 |
| Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis | Journal of Immunology | 2004 | 292 |
| Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease | Cell Death and Differentiation | 2004 | 280 |
| Kommerell's diverticulum and right-sided aortic arch: a cohort study and review of the literature | Journal of Vascular Surgery | 2004 | 274 |
| Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study | Journal of Infectious Diseases | 2004 | 254 |
| Low-molecular-weight heparin as bridging anticoagulation during interruption of warfarin: assessment of a standardized periprocedural anticoagulation regimen | Archives of Internal Medicine | 2004 | 249 |
| The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 242 |
| Role of peripheral CRF signalling pathways in stress-related alterations of gut motility and mucosal function | Neurogastroenterology and Motility | 2004 | 239 |
| SARS among critical care nurses, Toronto | Emerging Infectious Diseases | 2004 | 237 |
| Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism | Journal of Immunology | 2004 | 215 |
| The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes | Journal of Virology | 2004 | 213 |
| Live Lactobacillus rhamnosus [corrected] is essential for the inhibitory effect on tumor necrosis factor alpha-induced interleukin-8 expression | Infection and Immunity | 2004 | 211 |
| Developing optimal search strategies for detecting clinically sound prognostic studies in MEDLINE: an analytic survey | BMC Medicine | 2004 | 207 |
