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| Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources | Nucleic Acids Research | 2019 | 333 |
| Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial | JAMA Psychiatry | 2019 | 238 |
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| HDL and Reverse Cholesterol Transport | Circulation Research | 2019 | 195 |
| Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant | JAMA Internal Medicine | 2019 | 156 |
| Past and Future Burden of Inflammatory Bowel Diseases Based on Modeling of Population-Based Data | Gastroenterology | 2019 | 132 |
| Mitochondria as central regulators of neural stem cell fate and cognitive function | Nature Reviews Neuroscience | 2019 | 125 |
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| A roadmap for implementation of patient-centered digital outcome measures in Parkinson's disease obtained using mobile health technologies | Movement Disorders | 2019 | 115 |
| Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial | Lancet, The | 2019 | 113 |
| Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability | New England Journal of Medicine | 2019 | 110 |
| Measurement Properties of Visual Analogue Scale, Numeric Rating Scale, and Pain Severity Subscale of the Brief Pain Inventory in Patients With Low Back Pain: A Systematic Review | Journal of Pain | 2019 | 99 |
| Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas | Nature Communications | 2019 | 95 |
| Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors | Cell Stem Cell | 2019 | 95 |
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| Advancing functional and translational microbiome research using meta-omics approaches | Microbiome | 2019 | 84 |
| Break out of the Classroom: The Use of Escape Rooms as an Alternative Teaching Strategy in Surgical Education | Journal of Surgical Education | 2019 | 83 |
| Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis | Annals of Surgery | 2019 | 82 |
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| Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA) | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2019 | 80 |
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