| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 3 | The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy | Nature | 2015 | 2,092 |
| 4 | The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update | Apoptosis: an International Journal on Programmed Cell Death | 2003 | 1,411 |
| 5 | Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers | Nature Medicine | 2009 | 1,293 |
| 6 | Strategies to Address Low Drug Solubility in Discovery and Development | Pharmacological Reviews | 2013 | 1,257 |
| 7 | Importing Mitochondrial Proteins: Machineries and Mechanisms | Cell | 2009 | 1,240 |
| 8 | FunRich: An open access standalone functional enrichment and interaction network analysis tool | Proteomics | 2015 | 1,193 |
| 9 | MR1 presents microbial vitamin B metabolites to MAIT cells | Nature | 2012 | 1,189 |
| 10 | Revisiting Cardiac Cellular Composition | Circulation Research | 2016 | 1,092 |
| 11 | Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer | Science Translational Medicine | 2016 | 1,086 |
| 12 | MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES | Lancet, The | 1989 | 1,073 |
| 13 | Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome | Cell | 2017 | 1,048 |
| 14 | Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system | European Journal of Pharmaceutical Sciences | 2006 | 1,016 |
| 15 | The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism | Immunity | 2013 | 1,002 |
| 16 | Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling | Genome Biology | 2016 | 971 |
| 17 | Follicular Helper T Cells | Annual Review of Immunology | 2016 | 962 |
| 18 | Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders | Nature Reviews Drug Discovery | 2009 | 946 |
| 19 | Perforin and granzymes: function, dysfunction and human pathology | Nature Reviews Immunology | 2015 | 941 |
| 20 | Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration | Nature | 2015 | 864 |
| 21 | Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection | Antimicrobial Agents and Chemotherapy | 2017 | 846 |
| 22 | Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture | Cell Stem Cell | 2011 | 827 |
| 23 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 816 |
| 24 | Activation and allosteric modulation of a muscarinic acetylcholine receptor | Nature | 2013 | 806 |
| 25 | Quantifiable predictive features define epitope-specific T cell receptor repertoires | Nature | 2017 | 788 |
| 26 | Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets | Nature Reviews Drug Discovery | 2011 | 776 |
| 27 | T-cell activation by transitory neo-antigens derived from distinct microbial pathways | Nature | 2014 | 758 |
| 28 | High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice | Circulation | 2017 | 754 |
| 29 | The Human Gut Microbiome – A Potential Controller of Wellness and Disease | Frontiers in Microbiology | 2018 | 753 |
| 30 | Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites | Nature Communications | 2015 | 733 |
| 31 | Interleukin-22: Immunobiology and Pathology | Annual Review of Immunology | 2015 | 724 |
| 32 | Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 721 |
| 33 | More than one reason to rethink the use of peptides in vaccine design | Nature Reviews Drug Discovery | 2007 | 718 |
| 34 | Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies | Advanced Drug Delivery Reviews | 2008 | 717 |
| 35 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 706 |
| 36 | The burgeoning family of unconventional T cells | Nature Immunology | 2015 | 684 |
| 37 | Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy | Cell | 2021 | 680 |
| 38 | AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth. | Plant Cell | 1996 | 664 |
| 39 | Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney | Nature Cell Biology | 2014 | 660 |
| 40 | BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis | Science | 2018 | 657 |
| 41 | Aromatase—A Brief Overview | Annual Review of Physiology | 2002 | 650 |
| 42 | A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation | Nature Neuroscience | 2019 | 650 |
| 43 | Signalling bias in new drug discovery: detection, quantification and therapeutic impact | Nature Reviews Drug Discovery | 2013 | 641 |
| 44 | T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules | Annual Review of Immunology | 2015 | 641 |
| 45 | Tumor Necrosis Factor-α Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2) | Journal of Biological Chemistry | 2005 | 633 |
| 46 | MUSTANG: A multiple structural alignment algorithm | Proteins: Structure, Function and Bioinformatics | 2006 | 630 |
| 47 | Allosteric Modulation of G Protein–Coupled Receptors | Annual Review of Pharmacology and Toxicology | 2007 | 628 |
| 48 | Immune self-reactivity triggered by drug-modified HLA-peptide repertoire | Nature | 2012 | 628 |
| 49 | The dynamics of molecular evolution over 60,000 generations | Nature | 2017 | 624 |
| 50 | Control of flower development in Arabidopsis thaliana by APETALA1 and interacting genes | Development (Cambridge) | 1993 | 624 |
