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| 2 | Human Papillomavirus Type 16 E7 Oncoprotein Associates with the Cullin 2 Ubiquitin Ligase Complex, Which Contributes to Degradation of the Retinoblastoma Tumor Suppressor | Journal of Virology | 2007 | 266 |
| 3 | Essential role of Jun family transcription factors in PU.1 knockdown–induced leukemic stem cells | Nature Genetics | 2006 | 173 |
| 4 | NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 156 |
| 5 | Higher C-Reactive Protein Levels Predict Postoperative Delirium in Older Patients Undergoing Major Elective Surgery: A Longitudinal Nested Case-Control Study | Biological Psychiatry | 2017 | 123 |
| 6 | High C‐Reactive Protein Predicts Delirium Incidence, Duration, and Feature Severity After Major Noncardiac Surgery | Journal of the American Geriatrics Society | 2017 | 123 |
| 7 | Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells | Blood | 2016 | 108 |
| 8 | Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor ? in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor ?B-mediated induction of the Ets transcription factor ESE-1 | Arthritis and Rheumatism | 2003 | 104 |
| 9 | A Novel Role for GADD45β as a Mediator of MMP-13 Gene Expression during Chondrocyte Terminal Differentiation | Journal of Biological Chemistry | 2005 | 98 |
| 10 | Multiple myeloma–related deregulation of bone marrow–derived CD34+ hematopoietic stem and progenitor cells | Blood | 2012 | 95 |
| 11 | Optimizing a Proteomics Platform for Urine Biomarker Discovery | Molecular and Cellular Proteomics | 2010 | 79 |
| 12 | Bench-to-bedside review: Future novel diagnostics for sepsis - a systems biology approach | Critical Care | 2013 | 61 |
| 13 | GADD45 Deregulation in Cancer: Frequently Methylated Tumor Suppressors and Potential Therapeutic Targets | Clinical Cancer Research | 2005 | 53 |
| 14 | Emerging Evidence of the Gut Microbiome in Chemotherapy: A Clinical Review | Frontiers in Oncology | 2021 | 42 |
| 15 | Genomics of Renal Cell Cancer: The Biology Behind and the Therapy Ahead | Clinical Cancer Research | 2007 | 40 |
| 16 | Grammar-based distance in progressive multiple sequence alignment | BMC Bioinformatics | 2008 | 39 |
| 17 | Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium | American Journal of Physiology - Heart and Circulatory Physiology | 2013 | 34 |
| 18 | Increased levels of circulating MMP3 correlate with severe rejection in face transplantation | Scientific Reports | 2018 | 26 |
| 19 | Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults | Alzheimer's and Dementia: Translational Research and Clinical Interventions | 2021 | 26 |
| 20 | Identification of a Novel Potential Biomarker in a Model of Hemorrhagic Shock and Valproic Acid Treatment | Journal of Surgical Research | 2010 | 23 |
| 21 | Preliminary Biomarkers for Identification of Human Ascending Thoracic Aortic Aneurysm | Journal of the American Heart Association | 2013 | 23 |
| 22 | Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart | Physiological Genomics | 2009 | 22 |
| 23 | Prevention of Nonimmunologic Loss of Transplanted Islets in Monkeys | American Journal of Transplantation | 2014 | 22 |
| 24 | Microarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female | Physiological Genomics | 2012 | 17 |
| 25 | Creating a “pro-survival” phenotype through epigenetic modulation | Surgery | 2012 | 16 |
| 26 | Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation | Scientific Data | 2019 | 16 |
| 27 | Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study | Frontiers in Immunology | 2021 | 16 |
| 28 | Methodologic considerations in the design and analysis of nested case-control studies: association between cytokines and postoperative delirium | BMC Medical Research Methodology | 2017 | 15 |
| 29 | Exisulind induces apoptosis in advanced myelodysplastic syndrome (MDS) and acute myeloid leukaemia/MDS | British Journal of Haematology | 2006 | 13 |
| 30 | Significant polyomic and functional upregulation of the PAPP‐A/IGFBP‐4/5/IGF‐1 axis in chronic rhinosinusitis with nasal polyps | International Forum of Allergy and Rhinology | 2020 | 13 |
| 31 | Metformin for treatment of cytopenias in children and young adults with Fanconi anemia | Blood Advances | 2022 | 13 |
| 32 | Inflammatory manifestations in patients with Shwachman–Diamond syndrome: A novel phenotype | American Journal of Medical Genetics, Part A | 2020 | 12 |
| 33 | Proteomic Identification of Interleukin-2 Therapy Response in Metastatic Renal Cell Cancer | Journal of Urology | 2008 | 11 |
| 34 | High-Multiplex Aptamer-Based Serum Proteomics to Identify Candidate Serum Biomarkers of Oral Squamous Cell Carcinoma | Cancers | 2023 | 8 |
| 35 | Spatial Differences in Cellular and Molecular Responses as a Function of the Material Used in Conduit-Mediated Repair and Autograft Treatment of Peripheral Nerve Injuries | Advanced Functional Materials | 2018 | 6 |
| 36 | Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock | Journal of Cardiovascular Translational Research | 2024 | 4 |
| 37 | A predictedFrancisella tularensisDXD-motif glycosyltransferase blocks immune activation | Virulence | 2019 | 3 |
| 38 | Relationship between cortical brain atrophy, delirium, and long-term cognitive decline in older surgical patients | Neurobiology of Aging | 2024 | 3 |
| 39 | Exisulind Selectively Induces Apoptosis Via C-Jun Kinase Activation in MDS and sAML/MDS. | Blood | 2005 | 0 |
| 40 | Selective isolation of vein graft endothelial and smooth muscle cells using laser capture microdissection for microarray gene analysis | FASEB Journal | 2009 | 0 |
| 41 | Pre‐diagnostic plasma inflammatory proteins and risk of hepatocellular carcinoma in three population‐based cohort studies from the United States and the United Kingdom | International Journal of Cancer | 2024 | 0 |
