# | Title | Journal | Year | Citations |
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|
1 | Chromatin Modifications and Their Function | Cell | 2007 | 9,419 |
2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
3 | Regulation of chromatin by histone modifications | Cell Research | 2011 | 4,648 |
4 | Cancer Epigenetics: From Mechanism to Therapy | Cell | 2012 | 2,609 |
5 | Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain | Nature | 2001 | 2,581 |
6 | Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Nature | 2012 | 2,205 |
7 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 2,028 |
8 | Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A | Nature | 1993 | 1,903 |
9 | Requirement of bic/microRNA-155 for Normal Immune Function | Science | 2007 | 1,803 |
10 | The CBP co-activator is a histone acetyltransferase | Nature | 1996 | 1,680 |
11 | Single-cell reconstruction of the early maternal–fetal interface in humans | Nature | 2018 | 1,665 |
12 | Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma | Cancer Cell | 2012 | 1,600 |
13 | Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes | Science | 2007 | 1,559 |
14 | Studies on ruminant saliva. 1. The composition and output of sheep's saliva | Biochemical Journal | 1948 | 1,520 |
15 | Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,514 |
16 | Mutation in the tau gene in familial multiple system tauopathy with presenile dementia | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 1,495 |
17 | Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease | Immunological Reviews | 2006 | 1,424 |
18 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,398 |
19 | Degenerate oligonucleotide-primed PCR: General amplification of target DNA by a single degenerate primer | Genomics | 1992 | 1,365 |
20 | Scatter factor is a fibroblast-derived modulator of epithelial cell mobility | Nature | 1987 | 1,303 |
21 | Retinoblastoma protein recruits histone deacetylase to repress transcription | Nature | 1998 | 1,190 |
22 | Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology | Bioinformatics | 2010 | 1,175 |
23 | Natural killer cells and pregnancy | Nature Reviews Immunology | 2002 | 1,099 |
24 | Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS | Nature Genetics | 2002 | 1,097 |
25 | Acetylation: a regulatory modification to rival phosphorylation? | EMBO Journal | 2000 | 1,050 |
26 | Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export | Nature | 2000 | 1,021 |
27 | Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success | Journal of Experimental Medicine | 2004 | 1,002 |
28 | Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups | Cancer Cell | 2015 | 974 |
29 | Gene map of the extended human MHC | Nature Reviews Genetics | 2004 | 973 |
30 | Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Nature | 1995 | 939 |
31 | Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo | Nature | 1984 | 906 |
32 | DNA methyltransferase Dnmt1 associates with histone deacetylase activity | Nature Genetics | 2000 | 899 |
33 | Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas | Acta Neuropathologica | 2012 | 888 |
34 | Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control | Nature | 2017 | 888 |
35 | Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity | Cell | 2021 | 878 |
36 | The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation | Journal of Biological Chemistry | 2003 | 866 |
37 | SARS-CoV-2 evolution during treatment of chronic infection | Nature | 2021 | 858 |
38 | Clinical Features and Natural History of von Hippel-Lindau Disease | QJM - Monthly Journal of the Association of Physicians | 1990 | 841 |
39 | Histone methylation in transcriptional control | Current Opinion in Genetics and Development | 2002 | 837 |
40 | Induction of Immunological Tolerance by Porcine Liver Allografts | Nature | 1969 | 825 |
41 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 816 |
42 | The order Herpesvirales | Archives of Virology | 2009 | 810 |
43 | IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia | Nature Immunology | 2012 | 796 |
44 | Dissecting the genomic complexity underlying medulloblastoma | Nature | 2012 | 781 |
45 | Appendix—Spectrum of horse-heart cytochrome c | Biochemical Journal | 1959 | 775 |
46 | Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity | Journal of Experimental Medicine | 2005 | 775 |
47 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 770 |
48 | Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence | EMBO Journal | 2002 | 768 |
49 | CD28 and CTLA‐4 coreceptor expression and signal transduction | Immunological Reviews | 2009 | 760 |
50 | Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor | Science | 2002 | 759 |