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#	Title	Journal	Year	Citations
1	Functional Redundancy-Induced Stability of Gut Microbiota Subjected to Disturbance	Trends in Microbiology	2016	484
2	Microbial diversity and metabolic networks in acid mine drainage habitats	Frontiers in Microbiology	2015	253
3	Antibiotic use and microbiome function	Biochemical Pharmacology	2017	248
4	A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri – Structural and Functional Insights	Frontiers in Microbiology	2020	199
5	Estimating the success of enzyme bioprospecting through metagenomics: current status and future trends	Microbial Biotechnology	2016	179
6	Novel Polyphenol Oxidase Mined from a Metagenome Expression Library of Bovine Rumen	Journal of Biological Chemistry	2006	174
7	Exploring the human microbiome from multiple perspectives: factors altering its composition and function	FEMS Microbiology Reviews	2017	125
8	The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects	Mucosal Immunology	2017	112
9	Determinants and Prediction of Esterase Substrate Promiscuity Patterns	ACS Chemical Biology	2018	110
10	Microbial stratification in low pH oxic and suboxic macroscopic growths along an acid mine drainage	ISME Journal	2014	107
11	Metabolic versatility of small archaea Micrarchaeota and Parvarchaeota	ISME Journal	2018	100
12	Bacterial population and biodegradation potential in chronically crude oil-contaminated marine sediments are strongly linked to temperature	Scientific Reports	2015	99
13	Gut Bacteria Metabolism Impacts Immune Recovery in HIV-infected Individuals	EBioMedicine	2016	97
14	Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis	Nature Catalysis	2020	96
15	Engineering the ligninolytic enzyme consortium	Trends in Biotechnology	2015	92
16	Gut microbiota disturbance during antibiotic therapy	Gut Microbes	2014	87
17	Functional consequences of microbial shifts in the human gastrointestinal tract linked to antibiotic treatment and obesity	Gut Microbes	2013	82
18	A Comparison of Molten Sn and Bi for Solid Oxide Fuel Cell Anodes	Journal of the Electrochemical Society	2010	64
19	Metaproteomics and metabolomics analyses of chronically petroleum‐polluted sites reveal the importance of general anaerobic processes uncoupled with degradation	Proteomics	2015	63
20	Functional microbiome deficits associated with ageing: Chronological age threshold	Aging Cell	2020	61
21	Biochemical Diversity of Carboxyl Esterases and Lipases from Lake Arreo (Spain): a Metagenomic Approach	Applied and Environmental Microbiology	2013	59
22	Rational Engineering of Multiple Active Sites in an Ester Hydrolase	Biochemistry	2018	59
23	Symbiosis between nanohaloarchaeon and haloarchaeon is based on utilization of different polysaccharides	Proceedings of the National Academy of Sciences of the United States of America	2020	58
24	Outstanding Properties and Performance of CaTi0.5Mn0.5O3–δ for Solar-Driven Thermochemical Hydrogen Production	Matter	2021	58
25	HIV infection results in metabolic alterations in the gut microbiota different from those induced by other diseases	Scientific Reports	2016	55
26	Favorable Redox Thermodynamics of SrTi_0.5Mn_0.5O_3−δ in Solar Thermochemical Water Splitting	Chemistry of Materials	2020	55
27	The COMBREX Project: Design, Methodology, and Initial Results	PLoS Biology	2013	54
28	Biodiversity for biocatalysis: A review of the α/β-hydrolase fold superfamily of esterases-lipases discovered in metagenomes	Biocatalysis and Biotransformation	2015	51
29	The favourable thermodynamic properties of Fe-doped CaMnO₃ for thermochemical heat storage	Journal of Materials Chemistry A	2020	46
30	Modulation of the activity and selectivity of the immobilized lipases by surfactants and solvents	Biochemical Engineering Journal	2015	43
31	A novel α-glucosidase from the acidophilic archaeon Ferroplasma acidiphilum strain Y with high transglycosylation activity and an unusual catalytic nucleophile	Biochemical Journal	2005	42
32	Pressure adaptation is linked to thermal adaptation in salt‐saturated marine habitats	Environmental Microbiology	2015	41
33	The Structure of Oxygen Vacancies in the Near-Surface of Reduced CeO2 (111) Under Strain	Frontiers in Chemistry	2019	37
34	Diversity of hydrolases from hydrothermal vent sediments of the Levante Bay, Vulcano Island (Aeolian archipelago) identified by activity-based metagenomics and biochemical characterization of new esterases and an arabinopyranosidase	Applied Microbiology and Biotechnology	2015	36
35	Stabilization of Immobilized Lipases by Intense Intramolecular Cross-Linking of Their Surfaces by Using Aldehyde-Dextran Polymers	International Journal of Molecular Sciences	2018	36
36	Identification and Characterization of Carboxyl Esterases of Gill Chamber-Associated Microbiota in the Deep-Sea Shrimp Rimicaris exoculata by Using Functional Metagenomics	Applied and Environmental Microbiology	2015	35
37	High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review	Combinatorial Chemistry and High Throughput Screening	2016	35
38	Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family	Biochemical Journal	2013	34
39	Nitrilotriacetic Amine-Functionalized Polymeric Core–Shell Nanoparticles as Enzyme Immobilization Supports	Biomacromolecules	2017	32
40	Sulfur Respiration in a Group of Facultatively Anaerobic Natronoarchaea Ubiquitous in Hypersaline Soda Lakes	Frontiers in Microbiology	2018	31
41	Extraction of polyphenols and synthesis of new activated carbon from spent coffee grounds	Scientific Reports	2019	30
42	Decoding the ocean's microbiological secrets for marine enzyme biodiscovery	FEMS Microbiology Letters	2019	28
43	A purple acidophilic di-ferric DNA ligase from Ferroplasma	Proceedings of the National Academy of Sciences of the United States of America	2008	27
44	Biochemical studies on a versatile esterase that is most catalytically active with polyaromatic esters	Microbial Biotechnology	2014	27
45	Effects of HIV, antiretroviral therapy and prebiotics on the active fraction of the gut microbiota	Aids	2018	26
46	Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment	ACS Nano	2020	24
47	Gene Sets for Utilization of Primary and Secondary Nutrition Supplies in the Distal Gut of Endangered Iberian Lynx	PLoS ONE	2012	24
48	Structural and Functional Characterization of a Ruminal β-Glycosidase Defines a Novel Subfamily of Glycoside Hydrolase Family 3 with Permuted Domain Topology	Journal of Biological Chemistry	2016	23
49	Organic-Solvent-Tolerant Carboxylic Ester Hydrolases for Organic Synthesis	Applied and Environmental Microbiology	2020	22
50	Computationally Driven Rational Design of Substrate Promiscuity on Serine Ester Hydrolases	ACS Catalysis	2021	21

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