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Top Articles

#TitleJournalYearCitations
1The CRISPR/Cas9 system for plant genome editing and beyondBiotechnology Advances20151,106
2The production of recombinant pharmaceutical proteins in plantsNature Reviews Genetics2003868
3TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cellsLife Science Alliance2020737
4Molecular farming in plants: host systems and expression technologyTrends in Biotechnology2003655
5Nrf2, the Master Regulator of Anti-Oxidative ResponsesInternational Journal of Molecular Sciences2017629
6Plant-based production of biopharmaceuticalsCurrent Opinion in Plant Biology2004585
7Mitochondrial composition and function under the control of hypoxiaRedox Biology2017566
8Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids (8 pp)Environmental Science and Pollution Research2006559
9Plant cell cultures for the production of recombinant proteinsNature Biotechnology2004541
10Perfluoroalkyl and polyfluoroalkyl substances in consumer productsEnvironmental Science and Pollution Research2015536
11Cultivation of an obligate acidophilic ammonia oxidizer from a nitrifying acid soilProceedings of the National Academy of Sciences of the United States of America2011510
12Pesticide soil sorption parameters: theory, measurement, uses, limitations and reliabilityPest Management Science2002478
13Fate and Bioavailability of Engineered Nanoparticles in Soils: A ReviewCritical Reviews in Environmental Science and Technology2014402
14Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosisRedox Biology2020331
15Identification of endocrine-disrupting effects in aquatic vertebrates and invertebrates: report from the European IDEA projectEcotoxicology and Environmental Safety2003322
16Sowing the seeds of success: pharmaceutical proteins from plantsCurrent Opinion in Biotechnology2005321
17Detection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleasesBiotechnology Advances2017318
18Molecular farming for new drugs and vaccinesEMBO Reports2005294
19Endosperm-Specific Co-Expression of Recombinant Soybean Ferritin and Aspergillus Phytase in Maize Results in Significant Increases in the Levels of Bioavailable IronPlant Molecular Biology2005261
20(null)Plant Molecular Biology2003250
21Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucensDevelopmental and Comparative Immunology2018250
22Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitroToxicology in Vitro2019244
23Cancer cell and macrophage cross-talk in the tumor microenvironmentCurrent Opinion in Pharmacology2017236
24Diversity, evolution and medical applications of insect antimicrobial peptidesPhilosophical Transactions of the Royal Society B: Biological Sciences2016230
25GMP issues for recombinant plant-derived pharmaceutical proteinsBiotechnology Advances2012219
26Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant ProteinsFrontiers in Plant Science2019219
27Case study: bioavailability of tin and tin compoundsEcotoxicology and Environmental Safety2003213
28Making sense of big data in health research: Towards an EU action planGenome Medicine2016211
29Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered NanomaterialsEnvironmental Science & Technology2016210
30Progress in plant metabolic engineeringCurrent Opinion in Biotechnology2004209
31The early research and development of ebselenBiochemical Pharmacology2013208
32Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagyNature Communications2019202
33Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2and CytokinesMediators of Inflammation2017186
34Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future PotentialsCancers2019185
35Brief clinical evaluation of six high-throughput SARS-CoV-2 IgG antibody assaysJournal of Clinical Virology2020185
36Plants as sources of natural and recombinant anti-cancer agentsBiotechnology Advances2018184
37Taraxacum officinale and related species—An ethnopharmacological review and its potential as a commercial medicinal plantJournal of Ethnopharmacology2015180
38Challenges and advances in the heterologous expression of cellulolytic enzymes: a reviewBiotechnology for Biofuels2014173
39Adapting OECD Aquatic Toxicity Tests for Use with Manufactured Nanomaterials: Key Issues and Consensus RecommendationsEnvironmental Science & Technology2015173
40Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sextaInsect Biochemistry and Molecular Biology2016171
41Improving target assessment in biomedical research: the GOT-IT recommendationsNature Reviews Drug Discovery2020171
42Human biomonitoring of per- and polyfluoroalkyl substances in German blood plasma samples from 1982 to 2019Environment International2020169
43Patterns of CRISPR/Cas9 activity in plants, animals and microbesPlant Biotechnology Journal2016168
44THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitroMolecular Immunology2017167
45Ceramides as Novel Disease BiomarkersTrends in Molecular Medicine2019167
46Plant Molecular Pharming for the Treatment of Chronic and Infectious DiseasesAnnual Review of Plant Biology2014166
47Microbial degradation of nonylphenol and other alkylphenols—our evolving viewApplied Microbiology and Biotechnology2006165
48Sustainable farming of the mealworm Tenebrio molitor for the production of food and feedZeitschrift Fur Naturforschung - Section C Journal of Biosciences2017163
49Machine learning in pain researchPain2018161
50Influence of soil properties on the effect of silver nanomaterials on microbial activity in five soilsEnvironmental Pollution2015155