8.4K(top 0.1%)
PR articles
175.7K(top 1%)
PR citations
139(top 1%)
PR h-index
145(top 1%)
h-index
9.6K
documents
232.8K
doc citations
10.3K
citing journals

Top Articles

#TitleJournalYearCitations
1Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 studyLancet, The20211,206
2Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21Gastroenterology2017807
3Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancerNature Communications2022685
4Subchondral bone in osteoarthritis: insight into risk factors and microstructural changesArthritis Research and Therapy2013636
5Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune EvasionCancer Cell2020604
6Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat modelTheranostics2017589
7Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer MetastasisCancer Research2018563
8Alloying design of biodegradable zinc as promising bone implants for load-bearing applicationsNature Communications2020558
9Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric CancerJAMA - Journal of the American Medical Association2019523
10Collagen Tissue Engineering: Development of Novel Biomaterials and ApplicationsPediatric Research2008482
11METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancerMolecular Cancer2019446
12Identification of SARS-CoV-2 inhibitors using lung and colonic organoidsNature2020439
13Exosomes Secreted by Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Repair Critical-Sized Bone Defects through Enhanced Angiogenesis and Osteogenesis in Osteoporotic RatsInternational Journal of Biological Sciences2016428
14Vascularized 3D printed scaffolds for promoting bone regenerationBiomaterials2019427
15Obesity and Risk of Colorectal Cancer: A Systematic Review of Prospective StudiesPLoS ONE2013426
16Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancerNature Communications2023400
17Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regenerationNanoscale2017389
18Three-Column Fixation for Complex Tibial Plateau FracturesJournal of Orthopaedic Trauma2010376
19Injectable Stem Cell‐Laden Photocrosslinkable Microspheres Fabricated Using Microfluidics for Rapid Generation of Osteogenic Tissue ConstructsAdvanced Functional Materials2016371
20Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironmentNature Communications2020352
21Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cellsBMC Cell Biology2008345
22Multifunctional Magnesium Organic Framework-Based Microneedle Patch for Accelerating Diabetic Wound HealingACS Nano2021340
23Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancerCell Host and Microbe2023334
24The cell biology of intervertebral disc aging and degenerationAgeing Research Reviews2007329
25Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytesActa Pharmaceutica Sinica B2019316
26Structure–Antibacterial Activity Relationships of Imidazolium-Type Ionic Liquid Monomers, Poly(ionic liquids) and Poly(ionic liquid) Membranes: Effect of Alkyl Chain Length and CationsACS Applied Materials & Interfaces2016310
27TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental ColitisGastroenterology2013308
28LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification PatternCancer Discovery2016308
29An injectable self-healing coordinative hydrogel with antibacterial and angiogenic properties for diabetic skin wound repairNPG Asia Materials2019301
30Intercellular mitochondrial transfer as a means of tissue revitalizationSignal Transduction and Targeted Therapy2021295
31IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1LImmunity2014293
32A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1Cell Research2008292
33Minimally Invasive Surgery and the Novel Coronavirus Outbreak: Lessons Learned in China and ItalyAnnals of Surgery2020286
34Long-term Efficacy of Neoadjuvant Chemoradiotherapy Plus Surgery for the Treatment of Locally Advanced Esophageal Squamous Cell CarcinomaJAMA Surgery2021282
35Deterministic reprogramming of neutrophils within tumorsScience2024282
36Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre studyLancet Oncology, The2012280
37YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinomaMolecular Cancer2019274
38Global, regional, and national burden of ischemic stroke, 1990–2021: an analysis of data from the global burden of disease study 2021EClinicalMedicine2024274
39Cell infiltrative hydrogel fibrous scaffolds for accelerated wound healingActa Biomaterialia2017271
40The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectivesSignal Transduction and Targeted Therapy2021267
41A Bifunctional Biomaterial with Photothermal Effect for Tumor Therapy and Bone RegenerationAdvanced Functional Materials2016263
42Hepatocellular carcinoma: signaling pathways and therapeutic advancesSignal Transduction and Targeted Therapy2025260
43METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesisNature Cell Biology2022259
44LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-MycNature Communications2019258
45Biodegradable Mg-Cu alloy implants with antibacterial activity for the treatment of osteomyelitis: In vitro and in vivo evaluationsBiomaterials2016253
46Preoperative pembrolizumab combined with chemoradiotherapy for oesophageal squamous cell carcinoma (PALACE-1)European Journal of Cancer2021251
47Enterotoxigenic Bacteroides fragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3pGastroenterology2021250
48Exudate Absorbing and Antimicrobial Hydrogel Integrated with Multifunctional Curcumin-Loaded Magnesium Polyphenol Network for Facilitating Burn Wound HealingACS Nano2023250
49Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degenerationJournal of Cellular and Molecular Medicine2018249
50Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancerJournal of Experimental and Clinical Cancer Research2019248