The regulation of the secondary metabolism of Streptomyces: new links and experimental advances | Natural Product Reports | 2011 | 334 |
Overcoming barriers to membrane protein structure determination | Nature Biotechnology | 2011 | 293 |
A diversity of assembly mechanisms of a generic amyloid fold | Molecular Cell | 2011 | 244 |
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2 | EMBO Journal | 2011 | 209 |
Conformational conversion during amyloid formation at atomic resolution | Molecular Cell | 2011 | 142 |
A machine learning-based method to improve docking scoring functions and its application to drug repurposing | Journal of Chemical Information and Modeling | 2011 | 138 |
Structural divergence of the rotary ATPases | Quarterly Reviews of Biophysics | 2011 | 106 |
Multilayer enzyme-coupled magnetic nanoparticles as efficient, reusable biocatalysts and biosensors | Nanoscale | 2011 | 99 |
Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner | Journal of Virology | 2011 | 90 |
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3 | Journal of Cell Science | 2011 | 89 |
Ligand binding to distinct states diverts aggregation of an amyloid-forming protein | Nature Chemical Biology | 2011 | 85 |
Understanding the complex mechanisms of β2-microglobulin amyloid assembly | FEBS Journal | 2011 | 84 |
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP) | Physical Chemistry Chemical Physics | 2011 | 83 |
Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1) | Journal of Biological Chemistry | 2011 | 82 |
Nature of the ferryl heme in compounds I and II | Journal of Biological Chemistry | 2011 | 81 |
Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin | Cell Death and Differentiation | 2011 | 72 |
Helix-mediated protein--protein interactions as targets for intervention using foldamers | Amino Acids | 2011 | 62 |
Stomatin-deficient cryohydrocytosis results from mutations in SLC2A1: a novel form of GLUT1 deficiency syndrome | Blood | 2011 | 61 |
Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel | Hepatology | 2011 | 59 |
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites | Molecular Microbiology | 2011 | 58 |
Degenerate RNA packaging signals in the genome of Satellite Tobacco Necrosis Virus: implications for the assembly of a T=1 capsid | Journal of Molecular Biology | 2011 | 57 |
Urea and guanidinium induced denaturation of a Trp-cage miniprotein | Journal of Physical Chemistry B | 2011 | 54 |
Simple rules for efficient assembly predict the layout of a packaged viral RNA | Journal of Molecular Biology | 2011 | 52 |
The oligomeric state and arrangement of the active bacterial translocon | Journal of Biological Chemistry | 2011 | 52 |
ReverseScreen3D: a structure-based ligand matching method to identify protein targets | Journal of Chemical Information and Modeling | 2011 | 51 |