Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response | Nature Genetics | 2009 | 507 |
A pH-triggered, fast-responding DNA hydrogel | Angewandte Chemie - International Edition | 2009 | 349 |
Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies | European Journal of Mass Spectrometry | 2009 | 293 |
Fibril fragmentation enhances amyloid cytotoxicity | Journal of Biological Chemistry | 2009 | 290 |
Predicting druggable binding sites at the protein-protein interface | Drug Discovery Today | 2009 | 230 |
Nucleolar targeting: the hub of the matter | EMBO Reports | 2009 | 223 |
An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms | Nature Structural and Molecular Biology | 2009 | 197 |
Synthesis of natural-product-like molecules with over eighty distinct scaffolds | Angewandte Chemie - International Edition | 2009 | 193 |
Production of self-assembling biomaterials for tissue engineering | Trends in Biotechnology | 2009 | 188 |
AAA+ Ring and linker swing mechanism in the dynein motor | Cell | 2009 | 174 |
Natural killer cell cytotoxicity: how do they pull the trigger? | Immunology | 2009 | 158 |
Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding | Nature Structural and Molecular Biology | 2009 | 137 |
Endonucleolytic initiation of mRNA decay in Escherichia coli | Progress in Molecular Biology and Translational Science | 2009 | 120 |
Tuning the elastic modulus of hydrated collagen fibrils | Biophysical Journal | 2009 | 118 |
Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction | Chemical Communications | 2009 | 113 |
A pH-Triggered, Fast-Responding DNA Hydrogel | Angewandte Chemie | 2009 | 108 |
Membrane permeabilization by Islet Amyloid Polypeptide | Chemistry and Physics of Lipids | 2009 | 106 |
Enamel matrix proteins; old molecules for new applications | Orthodontics and Craniofacial Research | 2009 | 87 |
A FERM domain autoregulates Drosophila myosin 7a activity | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 83 |
Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3 | Journal of Molecular Biology | 2009 | 74 |
A generic mechanism of beta2-microglobulin amyloid assembly at neutral pH involving a specific proline switch | Journal of Molecular Biology | 2009 | 73 |
Binding site similarity analysis for the functional classification of the protein kinase family | Journal of Chemical Information and Modeling | 2009 | 72 |
Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils | Journal of Molecular Biology | 2009 | 69 |
Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases | Journal of Medicinal Chemistry | 2009 | 68 |
The SAH domain extends the functional length of the myosin lever | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 64 |