Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 363 |
Folding versus aggregation: polypeptide conformations on competing pathways | Archives of Biochemistry and Biophysics | 2008 | 305 |
Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter | Science | 2008 | 290 |
Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy | Nature Genetics | 2008 | 220 |
Nanomechanical detection of antibiotic-mucopeptide binding in a model for superbug drug resistance | Nature Nanotechnology | 2008 | 166 |
Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction | Journal of the American Chemical Society | 2008 | 159 |
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins | Xenobiotica | 2008 | 158 |
Modus operandi of the bacterial RNA polymerase containing the sigma54 promoter-specificity factor | Molecular Microbiology | 2008 | 105 |
Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel | Hepatology | 2008 | 99 |
The three-dimensional structure of genomic RNA in bacteriophage MS2: implications for assembly | Journal of Molecular Biology | 2008 | 98 |
Effects of hydration on the mechanical response of individual collagen fibrils | Applied Physics Letters | 2008 | 91 |
Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation | Journal of Molecular Biology | 2008 | 90 |
Directed evolution of aldolases for exploitation in synthetic organic chemistry | Archives of Biochemistry and Biophysics | 2008 | 76 |
Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication | PLoS Pathogens | 2008 | 75 |
Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolution | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 63 |
A subset of IL-10-producing gammadelta T cells protect the liver from Listeria-elicited, CD8(+) T cell-mediated injury | European Journal of Immunology | 2008 | 58 |
Synthesis of functionalised aromatic oligamide rods | Organic and Biomolecular Chemistry | 2008 | 53 |
Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 51 |
A common beta-sheet architecture underlies in vitro and in vivo beta2-microglobulin amyloid fibrils | Journal of Biological Chemistry | 2008 | 48 |
Sensing of 5' monophosphate by Escherichia coli RNase G can significantly enhance association with RNA and stimulate the decay of functional mRNA transcripts in vivo | Molecular Microbiology | 2008 | 46 |
Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5'-leader | Rna | 2008 | 44 |
Detection of intermediates and kinetic control during assembly of bacteriophage P22 procapsid | Journal of Molecular Biology | 2008 | 40 |
Insights into virus capsid assembly from non-covalent mass spectrometry | Mass Spectrometry Reviews | 2008 | 40 |
Engineering a multi-nucleated myotube, the role of the actin cytoskeleton | Journal of Microscopy | 2008 | 38 |
Purification, characterization, and identification of a novel bifunctional catalase-phenol oxidase from Scytalidium thermophilum | Applied Microbiology and Biotechnology | 2008 | 36 |