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Top Articles

#TitleJournalYearCitations
1Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.Journal of Cell Biology19921,041
2Genome-wide association study identifies eight loci associated with blood pressureNature Genetics2009890
3Mechanisms underlying beneficial plant–fungus interactions in mycorrhizal symbiosisNature Communications2010821
4Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAsCell2011743
5Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and PathologyPhysiological Reviews2008665
6Y chromosome sequence variation and the history of human populationsNature Genetics2000621
7A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum CardiomyopathyCell2007615
8Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritisNature Medicine2005589
9Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKTJournal of Cell Biology2002545
10Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune responseNature2002514
11In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of MelanomaCell2011481
12Role of αvβ3 integrin in the activation of vascular endothelial growth factor receptor-2EMBO Journal1999476
13Genome-wide association study identifies susceptibility loci for IgA nephropathyNature Genetics2011468
14Sequence variants at the TERT-CLPTM1L locus associate with many cancer typesNature Genetics2009459
15Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogensNature Genetics2014458
16Mechanisms of Myofibroblast Activity and Phenotypic ModulationExperimental Cell Research1999450
17A Functional Genomics Approach Identifies Candidate Effectors from the Aphid Species Myzus persicae (Green Peach Aphid)PLoS Genetics2010372
18Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cellsGenes and Development2012371
19PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent EffectsCell2004369
20A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility lociNature Genetics2010354
21The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-MetNature2002345
22PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilizationDevelopment (Cambridge)2004342
23Hemopexin: Structure, Function, and RegulationDNA and Cell Biology2002339
24Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemiaBlood2012324
25Receptor Tyrosine Kinases and TLR/IL1Rs Unexpectedly Activate Myeloid Cell PI3Kγ, A Single Convergent Point Promoting Tumor Inflammation and ProgressionCancer Cell2011322
26Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: Role of membrane oxidative damageHepatology2000320
27The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fateFree Radical Biology and Medicine2012319
28Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphateNature2013313
29Clinical and molecular genetics of patients with the Carney–Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHDEuropean Journal of Human Genetics2007312
30Arbuscular Mycorrhizal Fungi Elicit a Novel Intracellular Apparatus in Medicago truncatula Root Epidermal Cells before Infection[W]Plant Cell2005302
31Sequence variant on 8q24 confers susceptibility to urinary bladder cancerNature Genetics2008298
32Silencing of Aphid Genes by dsRNA Feeding from PlantsPLoS ONE2011290
33What makes an urban bird?Global Change Biology2011288
34Before gene expression: early events in plant–insect interactionTrends in Plant Science2007285
35Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25− into CD25+ T regulatory cellsBlood2007281
36Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractorinessBlood2011277
37A polymorphic variation in a putative regulation box of the TNFA promoter regionImmunogenetics1994274
38Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase SignalingAnnual Review of Cell and Developmental Biology2003272
39The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone developmentJournal of Experimental Medicine2012269
40Prognostic factors and survival in children with perinatal HIV-1 infectionLancet, The1992262
41Urbanization drives cross‐taxon declines in abundance and diversity at multiple spatial scalesGlobal Change Biology2020257
42Plant volatiles: Production, function and pharmacologyNatural Product Reports2011256
43Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular CarcinogenesisCancer Cell2011255
44Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk AnalysisPLoS Genetics2012255
45Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosisBone2008249
46Nitric Oxide Reverts the Resistance to Doxorubicin in Human Colon Cancer Cells by Inhibiting the Drug EffluxCancer Research2005245
47Expression of Ghrelin and of the GH Secretagogue Receptor by Pancreatic Islet Cells and Related Endocrine TumorsJournal of Clinical Endocrinology and Metabolism2002239
48Stat3 controls lysosomal-mediated cell death in vivoNature Cell Biology2011239
49Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regionsBiological Psychiatry2004238
50Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28Nature Genetics2010238