Biomedical Sciences

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14.4K(top 1%)

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120(top 1%)

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315

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18.2K

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2.3K

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Top Articles

#	Title	Journal	Year	Citations
1	A ratchet-like inter-subunit reorganization of the ribosome during translocation	Nature	2000	783
2	Genome-wide analysis of transcriptional dependence and probable target sites for Abf1 and Rap1 in Saccharomyces cerevisiae	Nucleic Acids Research	2007	594
3	Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit	Science	2001	465
4	Hepatitis C Virus IRES RNA–Induced Changes in the Conformation of the 40S Ribosomal Subunit	journal of hand surgery Asian-Pacific volume, The	2018	410
5	Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution	Cell	2000	403
6	A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome	Nature	1995	397
7	Structure of the signal recognition particle interacting with the elongation-arrested ribosome	Nature	2004	388
8	Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice	Nature Genetics	1999	372
9	Temperature, Viral Genetics, and the Transmission of West Nile Virus by Culex pipiens Mosquitoes	PLoS Pathogens	2008	371
10	Structure of the Mammalian Mitochondrial Ribosome Reveals an Expanded Functional Role for Its Component Proteins	Cell	2003	320
11	Single-Particle Imaging of Macromolecules by Cryo-Electron Microscopy	Annual Review of Biophysics and Biomolecular Structure	2002	284
12	EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome	Nature Structural Biology	1999	283
13	Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process	EMBO Journal	2002	274
14	Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement	Cell	2003	274
15	The outs and ins of transposition: from Mu to Kangaroo	Nature Reviews Molecular Cell Biology	2003	273
16	The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli	Cell	2005	257
17	Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome	EMBO Reports	2004	243
18	Structure of the E. coli protein-conducting channel bound to a translating ribosome	Nature	2005	243
19	A cryo-electron microscopic study of ribosome-bound termination factor RF2	Nature	2003	234
20	Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM	Nature Structural and Molecular Biology	2004	221
21	Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome	Molecular Cell	2014	219
22	Brain-to-text: decoding spoken phrases from phone representations in the brain	Frontiers in Neuroscience	2015	211
23	The Polypeptide Tunnel System in the Ribosome and Its Gating in Erythromycin Resistance Mutants of L4 and L22	Molecular Cell	2001	192
24	New Insights Into CRASP-Mediated Complement Evasion in the Lyme Disease Enzootic Cycle	Frontiers in Cellular and Infection Microbiology	2020	184
25	Analysis of Constructed E Gene Mutants of Mouse Hepatitis Virus Confirms a Pivotal Role for E Protein in Coronavirus Assembly	Journal of Virology	1998	179
26	Neural correlate of the construction of sentence meaning	Proceedings of the National Academy of Sciences of the United States of America	2016	161
27	Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism	Genes, Brain and Behavior	2011	160
28	The Origin of COVID-19 and Why It Matters	American Journal of Tropical Medicine and Hygiene	2020	146
29	Toward the molecular structure of the mitochondrial channel, VDAC	Journal of Bioenergetics and Biomembranes	1992	143
30	Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution	EMBO Journal	2000	143
31	Visualizing tmRNA Entry into a Stalled Ribosome	Science	2003	142
32	A practical procedure for real-time functional mapping of eloquent cortex using electrocorticographic signals in humans	Epilepsy and Behavior	2009	141
33	The dynein heavy chain: structure, mechanics and evolution	Trends in Cell Biology	2001	130
34	RF3 Induces Ribosomal Conformational Changes Responsible for Dissociation of Class I Release Factors	Cell	2007	130
35	Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture	Biomedical Materials (Bristol)	2011	129
36	Interaction of Era with the 30S Ribosomal Subunit	Molecular Cell	2005	128
37	The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions	Nature Cell Biology	2007	120
38	Mechanism for the Disassembly of the Posttermination Complex Inferred from Cryo-EM Studies	Molecular Cell	2005	119
39	Role of thrombin receptor in breast cancer invasiveness	British Journal of Cancer	1999	113
40	Extensive role of the general regulatory factors, Abf1 and Rap1, in determining genome-wide chromatin structure in budding yeast	Nucleic Acids Research	2011	111
41	Kinesin 5–independent poleward flux of kinetochore microtubules in PtK1 cells	Journal of Cell Biology	2006	106
42	Sustained Levels of FGF2 Maintain Undifferentiated Stem Cell Cultures with Biweekly Feeding	PLoS ONE	2013	101
43	Host-range restriction of vaccinia virus E3L-specific deletion mutants	Virus Genes	1996	100
44	A Single Mammalian Mitochondrial Translation Initiation Factor Functionally Replaces Two Bacterial Factors	Molecular Cell	2008	94
45	Interaction of the G′ Domain of Elongation Factor G and the C-Terminal Domain of Ribosomal Protein L7/L12 during Translocation as Revealed by Cryo-EM	Molecular Cell	2005	93
46	Structural Aspects of RbfA Action during Small Ribosomal Subunit Assembly	Molecular Cell	2007	90
47	Genetic Influences on Mosquito Feeding Behavior and the Emergence of Zoonotic Pathogens	American Journal of Tropical Medicine and Hygiene	2007	90
48	Cryptosporidium parvum Cpn60 targets a relict organelle	Current Genetics	2003	88
49	Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments	Journal of Cell Biology	2009	83
50	Elongation Arrest by SecM via a Cascade of Ribosomal RNA Rearrangements	Molecular Cell	2006	79

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