| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Metabolomics activity screening for identifying metabolites that modulate phenotype | Nature Biotechnology | 2018 | 357 |
| 2 | Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity | Cell | 2017 | 343 |
| 3 | TNF-induced structural joint damage is mediated by IL-1 | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 275 |
| 4 | Proposal of a comprehensive definition of modified and other forms of mycotoxins including “masked” mycotoxins | Mycotoxin Research | 2014 | 275 |
| 5 | Green tea extract and (−)‐epigallocatechin‐3‐gallate, the major tea catechin, exert oxidant but lack antioxidant activities | FASEB Journal | 2005 | 266 |
| 6 | Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease | Journal of Cell Science | 1993 | 247 |
| 7 | Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization | Nature Communications | 2020 | 200 |
| 8 | Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression | Journal of Nutritional Biochemistry | 2011 | 191 |
| 9 | Nitrate and nitrite in the diet: How to assess their benefit and risk for human health | Molecular Nutrition and Food Research | 2015 | 178 |
| 10 | Estrogen-dependent and C-C chemokine receptor-2–dependent pathways determine osteoclast behavior in osteoporosis | Nature Medicine | 2009 | 173 |
| 11 | High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia | Blood | 2011 | 170 |
| 12 | Genotoxic effects of heavy metals: Comparative investigation with plant bioassays | Environmental and Molecular Mutagenesis | 1998 | 151 |
| 13 | Involvement of free radicals in ageing: a consequence or cause of senescence | British Medical Bulletin | 1993 | 144 |
| 14 | Are mitochondria a permanent source of reactive oxygen species? | Biochimica Et Biophysica Acta - Bioenergetics | 2000 | 138 |
| 15 | Valerenic acid potentiates and inhibits GABAA receptors: Molecular mechanism and subunit specificity | Neuropharmacology | 2007 | 138 |
| 16 | Structure–Activity Relationships of Targeted RuII(η6-p-Cymene) Anticancer Complexes with Flavonol-Derived Ligands | Journal of Medicinal Chemistry | 2012 | 135 |
| 17 | Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention trials | Mutation Research - Reviews in Mutation Research | 2001 | 133 |
| 18 | Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder | Chemical Communications | 2012 | 133 |
| 19 | A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 130 |
| 20 | Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations | Archives of Toxicology | 2011 | 129 |
| 21 | Spin trapping of lipid radicals with DEPMPO-derived spin traps: detection of superoxide, alkyl and alkoxyl radicals in aqueous and lipid phase | Free Radical Biology and Medicine | 2000 | 128 |
| 22 | Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing | Frontiers in Bioengineering and Biotechnology | 2020 | 126 |
| 23 | Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses | Archives of Toxicology | 2020 | 125 |
| 24 | Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research | Marine Drugs | 2010 | 124 |
| 25 | Investigation of the electrophysiological properties of enniatins | Archives of Biochemistry and Biophysics | 2004 | 119 |
| 26 | Grayanotoxin Poisoning: ‘Mad Honey Disease’ and Beyond | Cardiovascular Toxicology | 2012 | 118 |
| 27 | METLIN MS2 molecular standards database: a broad chemical and biological resource | Nature Methods | 2020 | 118 |
| 28 | Enhancement of Glutathione and γ-Glutamylcysteine Synthetase, the Rate Limiting Enzyme of Glutathione Synthesis, by Chemoprotective Plant-Derived Food and Beverage Components in the Human Hepatoma Cell Line HepG2 | Nutrition and Cancer | 2003 | 116 |
| 29 | Heme oxygenase 1 (HO‐1) regulates osteoclastogenesis and bone resorption | FASEB Journal | 2005 | 115 |
| 30 | Enniatin Exerts p53-Dependent Cytostatic and p53-Independent Cytotoxic Activities against Human Cancer Cells | Chemical Research in Toxicology | 2007 | 115 |
| 31 | Exposome-Scale Investigations Guided by Global Metabolomics, Pathway Analysis, and Cognitive Computing | Analytical Chemistry | 2017 | 110 |
| 32 | The Existence of a Lysosomal Redox Chain and the Role of Ubiquinone | Archives of Biochemistry and Biophysics | 2000 | 109 |
| 33 | H2O2 detection from intact mitochondria as a measure for one-electron reduction of dioxygen requires a non-invasive assay system11Dedicated to Prof. E. Elstner, on the occasion of his 60th anniversary. | Biochimica Et Biophysica Acta - Bioenergetics | 1999 | 108 |
| 34 | Synergistic estrogenic effects of Fusarium and Alternaria mycotoxins in vitro | Archives of Toxicology | 2017 | 107 |
| 35 | Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice | Hepatology | 2011 | 105 |
| 36 | Ultra-sensitive, stable isotope assisted quantification of multiple urinary mycotoxin exposure biomarkers | Analytica Chimica Acta | 2018 | 102 |
| 37 | First-in-class ruthenium anticancer drug (KP1339/IT-139) induces an immunogenic cell death signature in colorectal spheroids in vitro | Metallomics | 2019 | 99 |
| 38 | Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen | Free Radical Biology and Medicine | 1996 | 97 |
| 39 | Dihydrolipoic Acid Maintains Ubiquinone in the Antioxidant Active Form by Two-Electron Reduction of Ubiquinone and One-Electron Reduction of Ubisemiquinone | Archives of Biochemistry and Biophysics | 1999 | 97 |
| 40 | Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins | Analytical and Bioanalytical Chemistry | 2018 | 96 |
| 41 | A fiber-deprived diet disturbs the fine-scale spatial architecture of the murine colon microbiome | Nature Communications | 2019 | 92 |
| 42 | Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin α Isoforms 3 and 7 | Structure | 2015 | 91 |
| 43 | Aberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage | Cell Host and Microbe | 2021 | 90 |
| 44 | Risk assessment of dioxin contamination in human food | Food and Chemical Toxicology | 2002 | 88 |
| 45 | Pharmacological Properties of GABAA Receptors Containing γ1 Subunits | Molecular Pharmacology | 2006 | 84 |
| 46 | Clinical pharmacy activities in chronic kidney disease and end-stage renal disease patients: a systematic literature review | BMC Nephrology | 2011 | 82 |
| 47 | Mycotoxin risk assessment for consumers of groundnut in domestic markets in Nigeria | International Journal of Food Microbiology | 2017 | 82 |
| 48 | Personalizing health care: feasibility and future implications | BMC Medicine | 2013 | 81 |
| 49 | Cyclodepsipeptides - Potential Drugs and Lead Compounds in the Drug Development Process | Current Medicinal Chemistry | 2009 | 80 |
| 50 | Biomonitoring of Mycotoxins in Human Breast Milk: Current State and Future Perspectives | Chemical Research in Toxicology | 2016 | 80 |
