| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Smad-dependent and Smad-independent pathways in TGF-β family signalling | Nature | 2003 | 4,886 |
| 2 | TGF-β-induced epithelial to mesenchymal transition | Cell Research | 2009 | 2,347 |
| 3 | TGF-β signaling in tumor suppression and cancer progression | Nature Genetics | 2001 | 2,140 |
| 4 | SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS | Annual Review of Cell and Developmental Biology | 2005 | 1,702 |
| 5 | The Draft Genome of Ciona intestinalis : Insights into Chordate and Vertebrate Origins | Science | 2002 | 1,552 |
| 6 | The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6 | Cell | 1994 | 1,297 |
| 7 | Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging | Journal of Neuroscience | 2012 | 1,126 |
| 8 | Odorant-selective genes and neurons mediate olfaction in C. elegans | Cell | 1993 | 1,098 |
| 9 | The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo | Development (Cambridge) | 1995 | 1,062 |
| 10 | Transcriptional Activators of TGF-β Responses: Smads | Cell | 1998 | 1,040 |
| 11 | An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination | Nature Genetics | 1998 | 970 |
| 12 | Molecular control of endothelial cell behaviour during blood vessel morphogenesis | Nature Reviews Molecular Cell Biology | 2011 | 909 |
| 13 | Receptor-associated Mad homologues synergize as effectors of the TGF-β response | Nature | 1996 | 833 |
| 14 | Neurobiology of the Caenorhabditis elegans Genome | Science | 1998 | 828 |
| 15 | Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription | Nature | 1998 | 776 |
| 16 | Cellular and molecular analyses of vascular tube and lumen formation in zebrafish | Development (Cambridge) | 2005 | 768 |
| 17 | Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum | Development (Cambridge) | 1999 | 768 |
| 18 | Natural Variation in a Neuropeptide Y Receptor Homolog Modifies Social Behavior and Food Response in C. elegans | Cell | 1998 | 747 |
| 19 | Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene | Nature | 1997 | 723 |
| 20 | The branching programme of mouse lung development | Nature | 2008 | 716 |
| 21 | A circuit for navigation in Caenorhabditis elegans | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 707 |
| 22 | Midbrain development induced by FGF8 in the chick embryo | Nature | 1996 | 692 |
| 23 | A positive feedback loop coordinates growth and patterning in the vertebrate limb | Nature | 1994 | 668 |
| 24 | Interphase chromosomes undergo constrained diffusional motion in living cells | Current Biology | 1997 | 651 |
| 25 | Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver | Nature | 2015 | 620 |
| 26 | Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse | Development (Cambridge) | 1992 | 617 |
| 27 | The roles of FGFs in the early development of vertebrate limbs | Genes and Development | 1998 | 597 |
| 28 | Cardiac troponin T is essential in sarcomere assembly and cardiac contractility | Nature Genetics | 2002 | 576 |
| 29 | TGF-β signaling in cancer — a double-edged sword | Trends in Cell Biology | 2001 | 573 |
| 30 | Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation | Cell | 1997 | 565 |
| 31 | Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo | Genes and Development | 1999 | 563 |
| 32 | Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells | Nature Biotechnology | 2011 | 560 |
| 33 | FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations | Cell | 1994 | 559 |
| 34 | TGF- β signaling in cancer – a double-edged sword | Trends in Cell Biology | 2001 | 526 |
| 35 | odr-10 Encodes a Seven Transmembrane Domain Olfactory Receptor Required for Responses to the Odorant Diacetyl | Cell | 1996 | 519 |
| 36 | Functions of FGF signalling from the apical ectodermal ridge in limb development | Nature | 2002 | 509 |
| 37 | TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA | EMBO Journal | 2007 | 493 |
| 38 | The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation | Genes and Development | 1998 | 484 |
| 39 | Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors | Nature | 1997 | 478 |
| 40 | TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation | EMBO Journal | 2001 | 478 |
| 41 | Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies | Developmental Dynamics | 2007 | 467 |
| 42 | Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed | Development (Cambridge) | 1999 | 462 |
| 43 | Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis | Journal of Cell Biology | 1997 | 449 |
| 44 | APMLRARα transgene initiates murine acute promyelocytic leukemia | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 446 |
| 45 | Restricted Expression of Cardiac Myosin Genes Reveals Regulated Aspects of Heart Tube Assembly in Zebrafish | Developmental Biology | 1999 | 440 |
| 46 | Zika virus cell tropism in the developing human brain and inhibition by azithromycin | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 440 |
| 47 | Comparing genomic expression patterns across species identifies shared transcriptional profile in aging | Nature Genetics | 2004 | 438 |
| 48 | Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons | Neuron | 1996 | 431 |
| 49 | A Putative Cyclic Nucleotide–Gated Channel Is Required for Sensory Development and Function in C. elegans | Neuron | 1996 | 424 |
| 50 | Combinatorial Expression of TRPV Channel Proteins Defines Their Sensory Functions and Subcellular Localization in C. elegans Neurons | Neuron | 2002 | 422 |
