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Top Articles

#TitleJournalYearCitations
1Signatures of mutational processes in human cancerNature20137,134
2Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation CarriersJAMA - Journal of the American Medical Association20172,141
3Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trialLancet Oncology, The20151,919
4Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancerLancet, The20051,810
5Landscape of somatic mutations in 560 breast cancer whole-genome sequencesNature20161,620
6Genome-wide association study identifies novel breast cancer susceptibility lociNature20071,549
7Mutational Processes Molding the Genomes of 21 Breast CancersCell20121,390
8Genes that mediate breast cancer metastasis to the brainNature20091,365
9The landscape of cancer genes and mutational processes in breast cancerNature20121,194
10Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trialLancet, The20041,143
11Efficacy of MRI and Mammography for Breast-Cancer Screening in Women with a Familial or Genetic PredispositionNew England Journal of Medicine20041,073
12Association analysis identifies 65 new breast cancer risk lociNature20171,042
13Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working GroupAnnals of Oncology2020892
14Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆Annals of Oncology2021859
15Large-scale genotyping identifies 41 new loci associated with breast cancer riskNature Genetics2013800
16HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signaturesNature Medicine2017757
17Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer SubtypesAmerican Journal of Human Genetics2019755
18Treatment of Metastatic Renal Cell Carcinoma With Autologous T-Lymphocytes Genetically Retargeted Against Carbonic Anhydrase IX: First Clinical ExperienceJournal of Clinical Oncology2006658
19Breast Cancer after Prophylactic Bilateral Mastectomy in Women with a BRCA1 or BRCA2 MutationNew England Journal of Medicine2001623
20Long-Term Risk of Cardiovascular Disease in 10-Year Survivors of Breast CancerJournal of the National Cancer Institute2007604
21Complex landscapes of somatic rearrangement in human breast cancer genomesNature2009595
22Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target ToxicityMolecular Therapy2013561
23Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival PredictionPLoS ONE2010543
24Genomic Evolution of Breast Cancer Metastasis and RelapseCancer Cell2017515
25Genome-wide association study identifies five new breast cancer susceptibility lociNature Genetics2010511
26Gastrointestinal stromal tumours: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-upAnnals of Oncology2022485
27Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival SignalsCancer Cell2009484
28CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancerGenome Research2013448
29Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancerNature Genetics2015445
30Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer riskNature Genetics2017423
31Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarcheNature2014415
32Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerNature Genetics2013407
33Bone sarcomas: ESMO–EURACAN–GENTURIS–ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-upAnnals of Oncology2021383
34Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian CancerJAMA - Journal of the American Medical Association2015382
35Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancerNature Genetics2017374
36Pan-cancer landscape of homologous recombination deficiencyNature Communications2020371
37Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-upAnnals of Oncology2019369
38Pharmacological Effects of Formulation VehiclesClinical Pharmacokinetics2012358
39Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2Nature Genetics2009354
40Inhibiting CDK4/6 in Breast Cancer with Palbociclib, Ribociclib, and Abemaciclib: Similarities and DifferencesDrugs2020344
41A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based studyLancet Oncology, The2017343
42European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part IEuropean Urology2008340
43Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analysesNature Genetics2020335
44Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and PharmacogeneticsClinical Pharmacokinetics2018331
45Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of In Vitro Morphological SubtypesPLoS ONE2014320
46Lethal graft-versus-host disease in mouse models of T cell receptor gene therapyNature Medicine2010317
47Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma GroupEuropean Journal of Cancer2004315
48Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repairNature Genetics2015312
49Identification of ten variants associated with risk of estrogen-receptor-negative breast cancerNature Genetics2017309
50Selection of Bone Metastasis Seeds by Mesenchymal Signals in the Primary Tumor StromaCell2013308