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| 2 | RNA
m
6
A methylation regulates sorafenib resistance in liver cancer through
FOXO
3‐mediated autophagy | EMBO Journal | 2020 | 391 |
| 3 | Severe asthma: from characteristics to phenotypes to endotypes | Clinical and Experimental Allergy | 2012 | 301 |
| 4 | Upper Airway Stimulation for Obstructive Sleep Apnea: 5‐Year Outcomes | Otolaryngology - Head and Neck Surgery | 2018 | 292 |
| 5 | Increases in Bcl‐2 and cleavage of caspase‐1 and caspase‐3 in human brain after head injury | FASEB Journal | 1999 | 269 |
| 6 | Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group | Journal of the American Heart Association | 2018 | 260 |
| 7 | Heavy chain ferritin acts as an anti‐apoptotic gene that protects livers from ischemia‐reperfusion injury | FASEB Journal | 2003 | 193 |
| 8 | Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases | British Journal of Pharmacology | 2018 | 192 |
| 9 | Clinically distinct electroencephalographic phenotypes of early myoclonus after cardiac arrest | Annals of Neurology | 2016 | 182 |
| 10 | mTORC
1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in
IPF
fibroblasts | Aging Cell | 2016 | 170 |
| 11 | Mechanisms of hemolysis‐associated platelet activation | Journal of Thrombosis and Haemostasis | 2013 | 168 |
| 12 | Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors | Scientific Reports | 2013 | 143 |
| 13 | IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study | Epilepsia | 2014 | 139 |
| 14 | Effect of a multi-level intervention on nurse–patient communication in the intensive care unit: Results of the SPEACS trial | Heart and Lung: Journal of Acute and Critical Care | 2014 | 134 |
| 15 | Clinical outcomes among low‐titer group O whole blood recipients compared to recipients of conventional components in civilian trauma resuscitation | Transfusion | 2018 | 132 |
| 16 | Safety profile of uncrossmatched, cold‐stored, low‐titer, group O+ whole blood in civilian trauma patients | Transfusion | 2018 | 125 |
| 17 | Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia | British Journal of Haematology | 2014 | 108 |
| 18 | ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis | Aging Cell | 2018 | 105 |
| 19 | Loss‐of‐Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia | Hepatology | 2021 | 105 |
| 20 | Nurse-Led Intervention to Improve Surrogate Decision Making for Patients with Advanced Critical Illness | American Journal of Critical Care | 2012 | 99 |
| 21 | Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data | Vox Sanguinis | 2016 | 99 |
| 22 | Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers | EMBO Molecular Medicine | 2021 | 93 |
| 23 | Pulmonary embolism response teams: Purpose, evidence for efficacy, and future research directions | Research and Practice in Thrombosis and Haemostasis | 2019 | 91 |
| 24 | Treating OSA: Current and emerging therapies beyond CPAP | Respirology | 2017 | 88 |
| 25 | Gender, Sex Hormones and Pulmonary Hypertension | Pulmonary Circulation | 2013 | 87 |
| 26 | Influence of age on wound healing and fibrosis | Journal of Pathology | 2013 | 86 |
| 27 | Acute kidney injury in severe sepsis: Pathophysiology, diagnosis, and treatment recommendations | Journal of Veterinary Emergency and Critical Care | 2015 | 84 |
| 28 | Proteasome Inhibitor Carfilzomib-Based Therapy for Antibody-Mediated Rejection of the Pulmonary Allograft: Use and Short-Term Findings | American Journal of Transplantation | 2017 | 79 |
| 29 | Acute Respiratory Distress Syndrome: A Clinical Review | Pulmonary Circulation | 2011 | 76 |
| 30 | Comprehensive Clinical and Molecular Analysis of 12 Families with Type 1 Recessive Cutis Laxa | Human Mutation | 2013 | 76 |
| 31 | Caspase‐8 expression and proteolysis in human brain after severe head injury | FASEB Journal | 2003 | 72 |
| 32 | Activation of AMP‐activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness | FASEB Journal | 2020 | 69 |
| 33 | Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community‐Dwelling Older Adults: The Health, Aging, and Body Composition Study | Journal of the American Geriatrics Society | 2013 | 66 |
| 34 | Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice | Matrix Biology | 2014 | 62 |
| 35 | Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development | Epilepsia | 2015 | 62 |
| 36 | IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study | Epilepsia | 2015 | 62 |
| 37 | Upper Airway Stimulation for OSA | Otolaryngology - Head and Neck Surgery | 2016 | 62 |
| 38 | Follistatin‐like protein 1 enhances NLRP3 inflammasome‐mediated IL‐1β secretion from monocytes and macrophages | European Journal of Immunology | 2014 | 60 |
| 39 | Drug‐Associated Acute Kidney Injury Identified in the United States Food and Drug Administration Adverse Event Reporting System Database | Pharmacotherapy | 2018 | 57 |
| 40 | Drug management in acute kidney disease – Report of the Acute Disease Quality Initiative XVI meeting | British Journal of Clinical Pharmacology | 2018 | 53 |
| 41 | Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia | Transfusion | 2014 | 52 |
| 42 | Prevention of Cardiac Surgery-Associated Acute Kidney Injury | International Journal of Artificial Organs | 2008 | 50 |
| 43 | Increasing tacrolimus time-in-therapeutic range is associated with superior one-year outcomes in lung transplant recipients | American Journal of Transplantation | 2018 | 50 |
| 44 | Genetic determinants of haemolysis in sickle cell anaemia | British Journal of Haematology | 2013 | 49 |
| 45 | Atrial arrhythmias are associated with increased mortality in pulmonary arterial hypertension | Pulmonary Circulation | 2018 | 45 |
| 46 | Overview of Current Therapeutic Approaches for Pulmonary Hypertension | Pulmonary Circulation | 2011 | 44 |
| 47 | Association of a Home Monitoring Program With Interstage and Stage 2 Outcomes | Journal of the American Heart Association | 2019 | 42 |
| 48 | Hope and advance care planning in advanced cancer: Is there a relationship? | Cancer | 2022 | 39 |
| 49 | Validation of cardiogenic shock phenotypes in a mixed cardiac intensive care unit population | Catheterization and Cardiovascular Interventions | 2022 | 39 |
| 50 | Adherence to Pediatric Cardiac Arrest Guidelines Across a Spectrum of Fifty Emergency Departments: A Prospective, In Situ, Simulation‐based Study | Academic Emergency Medicine | 2018 | 38 |
