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Top Articles

#TitleJournalYearCitations
1Microglial M1/M2 polarization and metabolic statesBritish Journal of Pharmacology20161,776
2A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicalsEnvironment International2012402
3httk: R Package for High-Throughput ToxicokineticsJournal of Statistical Software2017316
4SHORT COMMUNICATION: Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-AmericansCarcinogenesis1993284
5Features of Microglia and Neuroinflammation Relevant to Environmental Exposure and NeurotoxicityInternational Journal of Environmental Research and Public Health2011280
6Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in DrosophilaCell1990268
7Smoking and Parkinson’s diseaseNeurology1999218
8Role of alpha‐1 antitrypsin in human health and diseaseJournal of Internal Medicine2014216
93D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory considerationClinical and Translational Science2021172
10Drug-activated nuclear receptors CAR and PXRAnnals of Medicine2003168
11Estrogen Activation of the Nuclear Orphan Receptor CAR (Constitutive Active Receptor) in Induction of the MouseCyp2b10GeneMolecular Endocrinology2000161
12Disposition and excretion of 2,3,7,8-tetrachlorodibenzofuran in the ratToxicology and Applied Pharmacology1980157
13Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbitalFEBS Letters2003154
145 Gene Expression during Mammalian MeiosisCurrent Topics in Developmental Biology1997137
15Respiratory Toxicity of Diacetyl in C57Bl/6 MiceToxicological Sciences2008125
16Zinc is essential for the transcription function of Nrf2 in human renal tubule cells in vitro and mouse kidney in vivo under the diabetic conditionJournal of Cellular and Molecular Medicine2014120
17Crystal structure of human catecholamine sulfotransferase 1 1Edited by R. HuberJournal of Molecular Biology1999119
18SWIFT-Active Screener: Accelerated document screening through active learning and integrated recall estimationEnvironment International2020117
19Prediction of Rodent Carcinogenesis: An Evaluation of Prechronic Liver Lesions as Forecasters of Liver Tumors in NTP Carcinogenicity StudiesToxicologic Pathology2004105
20Genetic toxicology in the 21st century: Reflections and future directionsEnvironmental and Molecular Mutagenesis201196
21Acetaminophen: enzymatic formation of a transient phenoxyl free radicalBiochemical Pharmacology198493
22Carcinogenesis Studies: Results of 398 Experiments on 104 Chemicals from the U. S. National Toxicology ProgramAnnals of the New York Academy of Sciences198892
23Differential Activity and Synthesis of Lactate Dehydrogenase Isozymes A (Muscle), B (Heart), and C (Testis) in Mouse Spermatogenic CellsBiology of Reproduction198988
24Xenobiotic Metabolism by Prostaglandin Endoperoxide SynthetaseDrug Metabolism Reviews198387
25Characterization of Fscl cDNA for a Mouse Sperm Fibrous Sheath Component1Biology of Reproduction199586
26Effects of Mono(2-Ethylhexyl) Phthalate, a Testicular Toxicant, on Follicle-Stimulating Hormone Binding to Membranes from Cultured Rat Sertoli Cells1Biology of Reproduction199385
27Metabolism of benzo (a) pyrene to reactive intermediate (S) via prostaglandin biosynthesisLife Sciences197878
28Cadmium Induces p53-Dependent Apoptosis in Human Prostate Epithelial CellsPLoS ONE201278
29Genomic Models of Short-Term Exposure Accurately Predict Long-Term Chemical Carcinogenicity and Identify Putative Mechanisms of ActionPLoS ONE201477
30Inhibition of spontaneous or angiotensin II-stimulated water intake by atrial natriuretic factorBrain Research Bulletin198573
31Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cellsProstaglandins198072
32When environmental chemicals act like uncontrolled medicineTrends in Endocrinology and Metabolism201372
331α,25‐Dihydroxyvitamin D3‐liganded vitamin D receptor increases expression and transport activity of P‐glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cellsJournal of Neurochemistry201269
34Estrogen receptor‐α mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17α‐hydroxylase/17,20 μlyase) expressionFASEB Journal200768
35Liposomal melatonin rescues methamphetamine‐elicited mitochondrial burdens, pro‐apoptosis, and dopaminergic degeneration through the inhibition PKCδ geneJournal of Pineal Research201562
36The interaction of Sertoli and Leydig cells in the testicular toxicity of tri-o-cresyl phosphateToxicology and Applied Pharmacology199061
37Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical ResearchEnvironmental Health Perspectives201560
38Meta-analysis of chromosomal aberrations as a biomarker of exposure in healthcare workers occupationally exposed to antineoplastic drugsMutation Research - Reviews in Mutation Research201960
39Central neuromodulation of gastric acid secretion by bombesin-like peptidesPeptides198559
40Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposureEnvironmental and Molecular Mutagenesis202058
412,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) in pregnant C57BL/6N mice: distribution to the embryo and excretionArchives of Toxicology198556
42Behavioral indices of neurotoxicity: What can be measured?Neurotoxicology and Teratology198756
43Heat-Shock Cognate Protein (hsc7l) and Related Proteins in Mouse Spermatogenic CellsBiology of Reproduction198956
44Reproductive assessment by continuous breeding: evolving study design and summaries of ninety studies.Environmental Health Perspectives199756
45Passage of Chemicals into Human and Animal Semen: Mechanisms and SignificanceCRC Critical Reviews in Toxicology198255
46Comparison of multiple parameters of rodent carcinogenicity and in vitro genetic toxicityEnvironmental Mutagenesis198655
47Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseasesGlia201452
482,3,7,8-Tetrachlorodibenzofuran tissue distribution and excretion in guinea pigsToxicology and Applied Pharmacology198151
49Studies of the mechanisms involved in the fate of prostacyclin (PGI2) and 06-keto-PGF1α in the pulmonary circulationProstaglandins197850
50Estrogen Activation of the Nuclear Orphan Receptor CAR (Constitutive Active Receptor) in Induction of the Mouse Cyp2b10 GeneMolecular Endocrinology200050