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| 2 | Molecular characterization of the mouse agouti locus | Cell | 1992 | 826 |
| 3 | Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species | Proceedings of the National Academy of Sciences of the United States of America | 1974 | 664 |
| 4 | A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism | Nature | 1993 | 420 |
| 5 | Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 274 |
| 6 | A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Development and definition of the system | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1977 | 245 |
| 7 | Synthesis of Ribonucleic Acid and Protein in Plasmid-Containing Minicells of
Escherichia coli
K-12 | Journal of Bacteriology | 1971 | 227 |
| 8 | Age-Associated Changes in the DNA of Mouse Tissue | Science | 1971 | 214 |
| 9 | Chromatin bodies: isolation, subfractionation and physical characterization | Nucleic Acids Research | 1976 | 211 |
| 10 | Intracellular Trafficking of Epidermal Growth Factor Family Ligands Is Directly Influenced by the pH Sensitivity of the Receptor/Ligand Interaction | Journal of Biological Chemistry | 1995 | 208 |
| 11 | The Evil proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development | Mechanisms of Development | 1997 | 167 |
| 12 | Glycerol permeabilities of fertilized and unfertilized mouse ova | The Journal of Experimental Zoology | 1980 | 150 |
| 13 | PHYSICAL STUDIES OF ISOLATED EUCARYOTIC NUCLEI | Journal of Cell Biology | 1972 | 138 |
| 14 | A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Utilization with a variety of mutagenic agents | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1977 | 137 |
| 15 | Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice | Mammalian Genome | 1997 | 129 |
| 16 | Genotoxicity of tobacco smoke and tobacco smoke condensate | Mutation Research - Reviews in Genetic Toxicology | 1983 | 128 |
| 17 | Factors affecting survival of mouse embryos during freezing and thawing | Experimental Cell Research | 1974 | 125 |
| 18 | GLUTARALDEHYDE FIXATION OF ISOLATED EUCARYOTIC NUCLEI | Journal of Cell Biology | 1973 | 121 |
| 19 | Deficiency of the β3 subunit of the type A γ–aminobutyric acid receptor causes cleft palate in mice | Nature Genetics | 1995 | 121 |
| 20 | VISUALIZATION OF FREEZING DAMAGE | Journal of Cell Biology | 1973 | 120 |
| 21 | Immunologic Deficiencies in Senescence | Journal of Immunology | 1972 | 113 |
| 22 | A cluster-gene: Evidence for one gene, one polypeptide, five enzymes | Biochemical and Biophysical Research Communications | 1977 | 110 |
| 23 | Phenotypic consequences of deletion of the gamma 3, alpha 5, or beta 3 subunit of the type A gamma-aminobutyric acid receptor in mice. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 107 |
| 24 | Conformational states of chromatin в bodies induced by urea | Nucleic Acids Research | 1977 | 106 |
| 25 | An oligopeptide transport gene from Candida albicans | Microbiology (United Kingdom) | 1997 | 100 |
| 26 | Nitrosocarbaryl as a Potent Mutagen of Environmental Significance | Nature | 1974 | 95 |
| 27 | Cell specificity in metabolic activation of aflatoxin B1 and benzo(a)pyrene to mutagens for mammalian cells | Nature | 1978 | 95 |
| 28 | Purification and characterization of ribulose-5-phosphate kinase from spinach | Archives of Biochemistry and Biophysics | 1986 | 91 |
| 29 | DNA repair in human progeroid cells | Biochemical and Biophysical Research Communications | 1974 | 89 |
| 30 | The Molecular Pathway for the Regulation of Phosphoribulokinase by Thioredoxin f | Journal of Biological Chemistry | 1996 | 88 |
| 31 | Classification of chemical agents as to their ability to induce long-or short-patch DNA repair in human cells | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1981 | 85 |
| 32 | Ultraviolet- and X-Ray-Induced Responses of a Deoxyribonucleic Acid Polymerase-Deficient Mutant of
Escherichia coli | Journal of Bacteriology | 1971 | 85 |
| 33 | Endonucleolytic Activity from Micrococcus luteus That Acts on -Ray-Induced Damage in Plasmid DNA of Escherichia coli Minicells | Proceedings of the National Academy of Sciences of the United States of America | 1972 | 84 |
| 34 | Regulation of Hemoglobin Synthesis in a Murine Erythroblastic Leukemic Cell: The Requirement for Replication to Induce Hemoglobin Synthesis | Proceedings of the National Academy of Sciences of the United States of America | 1974 | 84 |
| 35 | Characteristics and kinetics of subzero chilling injury in Drosophila embryos | Cryobiology | 1992 | 83 |
| 36 | Steps in DNA Chain Elongation and Joining after Ultra-violet Irradiation of Human Cells | International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine | 1972 | 82 |
| 37 | Induction of Auxotrophic Mutations by Treatment of Chinese Hamster Cells with 5-Bromodeoxyuridine and Black Light | Proceedings of the National Academy of Sciences of the United States of America | 1972 | 81 |
| 38 | Analyses of mutation in pSV2gpt-transformed CHO cells | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1986 | 81 |
| 39 | Detailed Comparative Map of Human Chromosome 19q and Related Regions of the Mouse Genome | Genomics | 1996 | 81 |
| 40 | Macromolecular Crystal Annealing: Overcoming Increased Mosaicity Associated with Cryocrystallography | Acta Crystallographica Section D: Biological Crystallography | 1998 | 81 |
| 41 | Ion-exclusion chromatography: Analysis and isolation of nucleic acid components, and influence of separation parameters | Archives of Biochemistry and Biophysics | 1972 | 79 |
| 42 | Crystal structure and mechanism of a carbon–carbon bond hydrolase | Structure | 1999 | 79 |
| 43 | Na+, K+-ATPase in HeLa cells after prolonged growth in low K+ or ouabain | Journal of Cellular Physiology | 1981 | 78 |
| 44 | Photoreactivation and Photoreactivating Enzyme Activity in an Order of Mammals (Marsupialia) | Nature | 1969 | 76 |
| 45 | The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals | Food and Cosmetics Toxicology | 1973 | 76 |
| 46 | Induction of translocations by cyclophosphamide in different germ cell stages of male mice: Cytological characterization and transmission | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1975 | 74 |
| 47 | Glutathione peroxidase activity and selenium concentration in the hearts of doxorubicin-treated rabbits | Journal of Molecular and Cellular Cardiology | 1978 | 73 |
| 48 | A cytological and genetic study of oogenesis in Drosophila melanogaster | Developmental Biology | 1973 | 72 |
| 49 | Timing of sperm penetration, pronuclear formation, pronuclear DNA synthesis, and first cleavage in naturally ovulated mouse eggs | The Journal of Experimental Zoology | 1977 | 70 |
| 50 | Identification of Residues of Spinach Thioredoxin f That Influence Interactions with Target Enzymes | Journal of Biological Chemistry | 1996 | 70 |
