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Top Articles

#TitleJournalYearCitations
1MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysisNature Methods20152,906
2An auxin-based degron system for the rapid depletion of proteins in nonplant cellsNature Methods20091,682
3Inhibition of Macroautophagy Triggers ApoptosisMolecular and Cellular Biology20051,580
4Sex Determination: Why So Many Ways of Doing It?PLoS Biology20141,135
5Autophagy Defends Cells Against Invading Group A StreptococcusScience20041,088
6The Selaginella Genome Identifies Genetic Changes Associated with the Evolution of Vascular PlantsScience2011867
7Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli NucleoidJournal of Bacteriology1999839
8A lipidome atlas in MS-DIAL 4Nature Biotechnology2020766
9Ch IP ‐Atlas: a data‐mining suite powered by full integration of public Ch IP ‐seq dataEMBO Reports2018731
10Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in DrosophilaGenetics2013624
11New topoisomerase essential for chromosome segregation in E. coliCell1990616
12Functional Dissection of the Tol2 Transposable Element Identified the Minimal cis-Sequence and a Highly Repetitive Sequence in the Subterminal Region Essential for TranspositionGenetics2006536
13Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flowJournal of Evolutionary Biology2017506
14Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformaticsNature Methods2017502
15An Nkx2-5/Bmp2/Smad1 Negative Feedback Loop Controls Heart Progenitor Specification and ProliferationCell2007490
16The CENP-H–I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeresNature Cell Biology2006478
17Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule InterfaceMolecular Cell2010469
18Dicer is essential for formation of the heterochromatin structure in vertebrate cellsNature Cell Biology2004460
19The Centromere: Chromatin Foundation for the Kinetochore MachineryDevelopmental Cell2014408
20Targeting neural circuitry in zebrafish using GAL4 enhancer trappingNature Methods2007400
21CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer KinetochoreCell2008394
22Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and consCell Communication and Signaling2022367
23Substrate-induced gene-expression screening of environmental metagenome libraries for isolation of catabolic genesNature Biotechnology2005353
24Staufen- and FMRP-Containing Neuronal RNPs Are Structurally and Functionally Related to Somatic P BodiesNeuron2006339
25A key genetic factor for fucosyllactose utilization affects infant gut microbiota developmentNature Communications2016336
26Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A NucleosomesCell2011333
27A blocked structure at the 5′ terminus of mRNA from cytoplasmic polyhedrosis virusNature1975329
28Meta‐Analysis of Gut Dysbiosis in Parkinson's DiseaseMovement Disorders2020321
29Identification and characterization of the high-affinity choline transporterNature Neuroscience2000317
30The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial ProteomicsCell2010305
31Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structureEMBO Journal2012300
32An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in RicePlant Cell2013273
33The Earth BioGenome Project 2020: Starting the clockProceedings of the National Academy of Sciences of the United States of America2022273
34The Minus 35-Recognition Region of Escherichia coli Sigma 70 is Inessential for Initiation of Transcription at an "Extended Minus 10" PromoterJournal of Molecular Biology1993264
35Scc1/Rad21/Mcd1 Is Required for Sister Chromatid Cohesion and Kinetochore Function in Vertebrate CellsDevelopmental Cell2001264
36A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organismsNature Methods2019264
37Transgenesis and Gene Trap Methods in Zebrafish by Using the Tol2 Transposable ElementMethods in Cell Biology2004260
38CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like FoldCell2012257
39Genotype by Environment Interaction and Genetic Correlation of the same Trait under Different EnvironmentsJapanese Journal of Genetics1962252
40Construction and Analysis of a Human-Chimpanzee Comparative Clone MapScience2002233
41Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1EMBO Journal2007222
42Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeEMBO Journal2001219
43An Arabidopsis jmjC domain protein protects transcribed genes from DNA methylation at CHG sitesEMBO Journal2009215
44Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathwayEMBO Journal2005213
45Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeastCellular and Molecular Life Sciences2011211
46Rapid genome reshaping by multiple-gene loss after whole-genome duplication in teleost fish suggested by mathematical modelingProceedings of the National Academy of Sciences of the United States of America2015210
47Nucleosomal arrays self‐assemble into supramolecular globular structures lacking 30‐nm fibersEMBO Journal2016206
48Rice germline‐specific Argonaute MEL1 protein binds to phasiRNAs generated from more than 700 lincRNAsPlant Journal2014205
49The human Nup107–160 nuclear pore subcomplex contributes to proper kinetochore functionsEMBO Journal2007204
50CENP-T provides a structural platform for outer kinetochore assemblyEMBO Journal2013202