| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Beware of q2! | Journal of Molecular Graphics and Modelling | 2002 | 3,295 |
| 2 | Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties | Molecules | 2010 | 2,923 |
| 3 | Machine learning for molecular and materials science | Nature | 2018 | 2,641 |
| 4 | Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases | Cancer Cell | 2011 | 2,430 |
| 5 | Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature | Natural Product Reports | 2013 | 1,755 |
| 6 | The Importance of Being Earnest: Validation is the Absolute Essential for Successful Application and Interpretation of QSPR Models | QSAR and Combinatorial Science | 2003 | 1,742 |
| 7 | Health benefits of dietary fiber | Nutrition Reviews | 2009 | 1,623 |
| 8 | QSAR Modeling: Where Have You Been? Where Are You Going To? | Journal of Medicinal Chemistry | 2014 | 1,475 |
| 9 | Exosomes as drug delivery vehicles for Parkinson's disease therapy | Journal of Controlled Release | 2015 | 1,468 |
| 10 | Best Practices for QSAR Model Development, Validation, and Exploitation | Molecular Informatics | 2010 | 1,428 |
| 11 | Pharmacokinetics and Biodistribution of Nanoparticles | Molecular Pharmaceutics | 2008 | 1,344 |
| 12 | Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology | Cancer Research | 2013 | 1,267 |
| 13 | Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense | Toxicology and Applied Pharmacology | 2005 | 1,238 |
| 14 | ANI-1: an extensible neural network potential with DFT accuracy at force field computational cost | Chemical Science | 2017 | 1,215 |
| 15 | Nanoparticles in the clinic: An update | Bioengineering and Translational Medicine | 2019 | 1,184 |
| 16 | Bioresponsive materials | Nature Reviews Materials | 2017 | 1,175 |
| 17 | Psychedelics | Pharmacological Reviews | 2016 | 1,117 |
| 18 | Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells | Nanomedicine: Nanotechnology, Biology, and Medicine | 2016 | 1,083 |
| 19 | Impact of high-throughput screening in biomedical research | Nature Reviews Drug Discovery | 2011 | 1,044 |
| 20 | Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells | Archives of Toxicology | 2000 | 894 |
| 21 | The Flipped Classroom | Academic Medicine | 2014 | 871 |
| 22 | Medical Therapy for Heart Failure With Reduced Ejection Fraction | Journal of the American College of Cardiology | 2018 | 853 |
| 23 | Using exosomes, naturally-equipped nanocarriers, for drug delivery | Journal of Controlled Release | 2015 | 821 |
| 24 | Deep reinforcement learning for de novo drug design | Science Advances | 2018 | 808 |
| 25 | Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin | Clinical Pharmacology and Therapeutics | 2008 | 753 |
| 26 | The promise and peril of chemical probes | Nature Chemical Biology | 2015 | 719 |
| 27 | Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 686 |
| 28 | The delivery of therapeutic oligonucleotides | Nucleic Acids Research | 2016 | 683 |
| 29 | The evolution of commercial drug delivery technologies | Nature Biomedical Engineering | 2021 | 679 |
| 30 | Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer | Cell | 2012 | 652 |
| 31 | Neural correlates of the LSD experience revealed by multimodal neuroimaging | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 652 |
| 32 | Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research | Journal of Chemical Information and Modeling | 2010 | 648 |
| 33 | Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody | Nano Letters | 2016 | 645 |
| 34 | Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis | Gene Therapy | 2001 | 639 |
| 35 | The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution | Molecular Endocrinology | 2000 | 613 |
| 36 | Capecitabine: A review | Clinical Therapeutics | 2005 | 606 |
| 37 | International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP) | Pharmacotherapy | 2019 | 603 |
| 38 | Rational selection of training and test sets for the development of validated QSAR models | Journal of Computer-Aided Molecular Design | 2003 | 600 |
| 39 | ATP-triggered anticancer drug delivery | Nature Communications | 2014 | 591 |
| 40 | DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility | Annual Review of Pharmacology and Toxicology | 2015 | 565 |
| 41 | Endocrine Regulation of Male Fertility by the Skeleton | Cell | 2011 | 560 |
| 42 | A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly outpatients with polypharmacy | American Journal of Medicine | 1996 | 557 |
| 43 | In vivo delivery of miRNAs for cancer therapy: Challenges and strategies | Advanced Drug Delivery Reviews | 2015 | 557 |
| 44 | Recent Advances in Nonviral Vectors for Gene Delivery | Accounts of Chemical Research | 2012 | 554 |
| 45 | microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7 | Journal of Cell Biology | 2010 | 541 |
| 46 | Beware of R2: Simple, Unambiguous Assessment of the Prediction Accuracy of QSAR and QSPR Models | Journal of Chemical Information and Modeling | 2015 | 529 |
| 47 | Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing | Angewandte Chemie - International Edition | 2015 | 528 |
| 48 | Recent advances of cocktail chemotherapy by combination drug delivery systems | Advanced Drug Delivery Reviews | 2016 | 522 |
| 49 | Anticancer Platelet‐Mimicking Nanovehicles | Advanced Materials | 2015 | 520 |
| 50 | mRNA vaccine for cancer immunotherapy | Molecular Cancer | 2021 | 519 |
