A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection. | Cell Reports | 2022 | 10 |
Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX. | British Journal of Pharmacology | 2022 | 10 |
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. | ELife | 2022 | 10 |
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity. | Journal of Virology | 2022 | 7 |
SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses. | Cell Reports | 2022 | 6 |
Identification and characterization of the interaction between the methyl-7-guanosine cap maturation enzyme RNMT and the cap-binding protein eIF4E. | Journal of Molecular Biology | 2022 | 4 |
The HIV-1 proviral landscape reveals Nef contributes to HIV-1 persistence in effector memory CD4+ T-cells. | Journal of Clinical Investigation | 2022 | 4 |
Common coupling map advances GPCR-G protein selectivity. | ELife | 2022 | 4 |
DICAM promotes T17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation. | Science Translational Medicine | 2022 | 3 |
First-in-human immunoPET imaging of HIV-1 infection using Zr-labeled VRC01 broadly neutralizing antibody. | Nature Communications | 2022 | 3 |
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer. | Nature Chemical Biology | 2022 | 3 |
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription. | PLoS Pathogens | 2022 | 2 |
UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells. | Stem Cell Research and Therapy | 2022 | 2 |
Clinical Reasoning Behind Antibiotic Use in PICUs: A Qualitative Study. | Pediatric Critical Care Medicine | 2022 | 2 |
Nitric oxide stimulates type IV MSHA pilus retraction in via activation of the phosphodiesterase CdpA. | Proceedings of the National Academy of Sciences of the United States of America | 2022 | 2 |
CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia. | EMBO Molecular Medicine | 2022 | 2 |
The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites. | Nature Communications | 2022 | 2 |
Detection of the HIV-1 accessory proteins Nef and Vpu by flow cytometry represents a new tool to study their functional interplay within a single infected CD4+ T cell. | Journal of Virology | 2022 | 1 |
Signaling by the tyrosine kinase Yes promotes liver cancer development. | Science Signaling | 2022 | 1 |
Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes. | EMBO Journal | 2022 | 1 |
Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants | ACS Pharmacology and Translational Science | 2022 | 1 |
Humoral Immunity to Allogeneic Immunoproteasome-Expressing Mesenchymal Stromal Cells Requires Efferocytosis by Endogenous Phagocytes. | Cells | 2022 | 1 |
Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8 T-Cell Behaviors | Neurology: Neuroimmunology and NeuroInflammation | 2022 | 1 |
Functional diversity in the RAS subfamily of small GTPases. | Biochemical Society Transactions | 2022 | 1 |
Chapter 3: Diagnosis of tuberculosis disease and drug-resistant tuberculosis | Canadian Journal of Respiratory, Critical Care, and Sleep Medicine | 2022 | 1 |