| 1 | The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions | Protein Science | 2021 | 1,580 |
| 2 | CXCL13 is a plasma biomarker of germinal center activity | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 375 |
| 3 | IL‐15: a central regulator of celiac disease immunopathology | Immunological Reviews | 2014 | 216 |
| 4 | Community guidelines for GPCR ligand bias: IUPHAR review 32 | British Journal of Pharmacology | 2022 | 187 |
| 5 | Drosophila S2 Cells Secrete Wingless on Exosome‐Like Vesicles but the Wingless Gradient Forms Independently of Exosomes | Traffic | 2013 | 169 |
| 6 | Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation | Annals of Neurology | 2013 | 146 |
| 7 | MEK drives BRAF activation through allosteric control of KSR proteins | Nature | 2018 | 139 |
| 8 | Initial steps of the pathogenesis of the infection caused byStreptococcus suis: fighting against nonspecific defenses | FEBS Letters | 2016 | 136 |
| 9 | Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children | Science | 2023 | 132 |
| 10 | Lifelong leukocyte telomere dynamics and survival in a free-living mammal | Aging Cell | 2016 | 131 |
| 11 | Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation | EMBO Journal | 2001 | 110 |
| 12 | Natural Health Products, Modulation of Immune Function and Prevention of Chronic Diseases | Evidence-based Complementary and Alternative Medicine | 2005 | 105 |
| 13 | Accidental exposures to peanut in a large cohort of Canadian children with peanut allergy | Clinical and Translational Allergy | 2015 | 98 |
| 14 | Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance | Immunological Reviews | 2017 | 98 |
| 15 | Antibacterial electrospun chitosan‐based nanofibers: A bacterial membrane perforator | Food Science and Nutrition | 2017 | 92 |
| 16 | Revertants of v-fos-transformed fibroblasts have mutations in cellular genes essential for transformation by other oncogenes | Cell | 1987 | 87 |
| 17 | Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging | Cytoskeleton | 2013 | 84 |
| 18 | Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response | Nature Communications | 2020 | 83 |
| 19 | Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3 | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 81 |
| 20 | Comparison of the MHC I Immunopeptidome Repertoire of B‐Cell Lymphoblasts Using Two Isolation Methods | Proteomics | 2018 | 72 |
| 21 | Systematic protein–protein interaction mapping for clinically relevant human GPCRs | Molecular Systems Biology | 2017 | 70 |
| 22 | Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors | Oncogene | 2010 | 67 |
| 23 | The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled | Immunological Reviews | 2015 | 66 |
| 24 | TRAPPC11 functions in autophagy by recruiting ATG2B‐WIPI4/WDR45 to preautophagosomal membranes | Traffic | 2019 | 65 |
| 25 | Computational pathology: A survey review and the way forward | Journal of Pathology Informatics | 2024 | 65 |
| 26 | SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells | PLoS Genetics | 2014 | 64 |
| 27 | HIV‐1 viral protein R causes peripheral nervous system injury associated with
in vivo
neuropathic pain | FASEB Journal | 2010 | 63 |
| 28 | Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV‐infected patients receiving antiretroviral therapy | HIV Medicine | 2015 | 62 |
| 29 | Phosphoproteome dynamics of
Saccharomyces cerevisiae
under heat shock and cold stress | Molecular Systems Biology | 2015 | 59 |
| 30 | Celastrol protects ischaemic myocardium through a heat shock response with up‐regulation of haeme oxygenase‐1 | British Journal of Pharmacology | 2014 | 58 |
| 31 | CNIH4 Interacts with Newly Synthesized GPCR and Controls Their Export from the Endoplasmic Reticulum | Traffic | 2014 | 58 |
| 32 | Enhancement of mass spectrometry performance for proteomic analyses using high‐field asymmetric waveform ion mobility spectrometry (FAIMS) | Journal of Mass Spectrometry | 2015 | 41 |
| 33 | Honey and Nigella sativa against COVID‐19 in Pakistan (HNS‐COVID‐PK): A multicenter placebo‐controlled randomized clinical trial | Phytotherapy Research | 2023 | 41 |
| 34 | DIAGNOSIS OF VIRAL RESPIRATORY INFECTIONS BY ELECTRON MICROSCOPY | Lancet, The | 1969 | 36 |
| 35 | A defect in ATP‐citrate lyase links acetyl‐CoA production, virulence factor elaboration and virulence in Cryptococcus neoformans | Molecular Microbiology | 2012 | 35 |
| 36 | IL‐2 and IL‐15 regulate CD8+ memory T‐cell differentiation but are dispensable for protective recall responses | European Journal of Immunology | 2015 | 34 |
| 37 | Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts | American Journal of Transplantation | 2020 | 33 |
| 38 | Protein‐protein interactions monitored in cells from transgenic mice using bioluminescence resonance energy transfer | FASEB Journal | 2010 | 31 |
| 39 | Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML | | 2021 | 30 |
| 40 | Survival of enterohemorrhagic Escherichia coli in the presence of Acanthamoeba castellanii and its dependence on Pho regulon | MicrobiologyOpen | 2012 | 28 |
| 41 | Funding considerations for the disclosure of genetic incidental findings in biobank research | Clinical Genetics | 2013 | 27 |
| 42 | Can my child with IgE‐mediated peanut allergy introduce foods labeled with “may contain traces”? | Pediatric Allergy and Immunology | 2020 | 27 |
| 43 | Tieing together loose ends: telomere instability in cancer and aging | Molecular Oncology | 2022 | 27 |
| 44 | Molecular and genetic parameters defining T‐cell clonal selection | Immunology and Cell Biology | 2011 | 26 |
| 45 | CD5 levels define functionally heterogeneous populations of naïve human CD4+ T cells | European Journal of Immunology | 2021 | 26 |
| 46 | A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition | Aging Cell | 2021 | 26 |
| 47 | Hospital‐Acquired Phaeohyphomycosis Due to Exserohilum rostratum in a Child with Leukemia | Canadian Journal of Infectious Diseases and Medical Microbiology | 2007 | 25 |
| 48 | Encapsulated group BStreptococcusmodulates dendritic cell functions via lipid rafts and clathrin-mediated endocytosis | Cellular Microbiology | 2012 | 25 |
| 49 | Major multilevel molecular divergence between THP‐1 cells from different biorepositories | International Journal of Cancer | 2020 | 25 |
| 50 | β‐Blockers have differential effects on the murine asthma phenotype | British Journal of Pharmacology | 2015 | 24 |
