"Diabodies": small bivalent and bispecific antibody fragments | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 754 |
Overexpression of integral membrane proteins for structural studies | Quarterly Reviews of Biophysics | 1995 | 341 |
Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires | Nucleic Acids Research | 1993 | 152 |
A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1 | Biochemistry | 1997 | 127 |
Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane | Biochemical Journal | 1995 | 113 |
Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins | Journal of Biological Chemistry | 2004 | 97 |
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A | Journal of Molecular Biology | 2003 | 97 |
Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers | Journal of Biological Chemistry | 2009 | 96 |
Backbone-driven collapse in unfolded protein chains | Journal of Molecular Biology | 2011 | 89 |
Structural consequences of nucleophosmin mutations in acute myeloid leukemia | Journal of Biological Chemistry | 2008 | 84 |
A method for the selection of catalytic activity using phage display and proximity coupling | Angewandte Chemie - International Edition | 1999 | 72 |
Formation of short-lived protein aggregates directly from the coil in two-state folding | Biochemistry | 1999 | 72 |
Engineering bispecific antibodies | Current Opinion in Biotechnology | 1993 | 71 |
The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3 | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 70 |
Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents | Journal of Medicinal Chemistry | 2006 | 70 |
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells | Nucleic Acids Research | 2009 | 64 |
Rational design of a novel fluorescent biosensor for beta-lactam antibiotics from a class A beta-lactamase | Journal of the American Chemical Society | 2004 | 57 |
Local cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution | Journal of the American Chemical Society | 2010 | 49 |
Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding | Protein Science | 2010 | 47 |
Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis-Finnish type | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 47 |
Unsuspected control of siderophore production by N-acetylglucosamine in streptomycetes | Environmental Microbiology Reports | 2012 | 46 |
Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 38 |
Improving the display of proteins on filamentous phage | Research in Microbiology | 2001 | 38 |
Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2 | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 36 |
Three sisters, different names | Nature Structural Biology | 1994 | 28 |