EMT: 2016 | Cell | 2016 | 2.4K |
The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies | Annual Review of Pharmacology and Toxicology | 2016 | 156 |
The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway | Gut | 2016 | 140 |
Novel therapeutic targets on the horizon for lung cancer | Lancet Oncology, The | 2016 | 120 |
Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 63 |
p53 Maintains Genomic Stability by Preventing Interference between Transcription and Replication | Cell Reports | 2016 | 59 |
MELK is an oncogenic kinase essential for early hepatocellular carcinoma recurrence | Cancer Letters | 2016 | 51 |
In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells | Journal of Pathology | 2016 | 45 |
Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 43 |
Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate | Angewandte Chemie - International Edition | 2016 | 29 |
Coverage analysis in a targeted amplicon-based next-generation sequencing panel for myeloid neoplasms | Journal of Clinical Pathology | 2016 | 25 |
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia | Clinical Cancer Research | 2016 | 20 |
Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells | Hepatology | 2016 | 17 |
Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate | Angewandte Chemie | 2016 | 13 |
Tpd3-Pph21 phosphatase plays a direct role in Sep7 dephosphorylation in Candida albicans | Molecular Microbiology | 2016 | 13 |
Novel actin filaments from Bacillus thuringiensis form nanotubules for plasmid DNA segregation | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 12 |
TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program | Journal of Molecular Cell Biology | 2016 | 12 |
Myelodysplastic features in a patient with germline CEBPA-mutant acute myeloid leukaemia | Journal of Clinical Pathology | 2016 | 8 |
Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease | Movement Disorders | 2016 | 8 |
The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity | FEBS Journal | 2016 | 8 |
Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding | Journal of Visualized Experiments | 2016 | 7 |
An Alternative Strategy for Pan-acetyl-lysine Antibody Generation | PLoS ONE | 2016 | 7 |
Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing | Archives of Biochemistry and Biophysics | 2016 | 7 |
Combination of ciclopirox olamine and sphingosine-1-phosphate as granulation enhancer in diabetic wounds | Wound Repair and Regeneration | 2016 | 6 |