Signal transduction by reactive oxygen species | Journal of Cell Biology | 2011 | 1.5K |
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) | Journal of Experimental Medicine | 2011 | 614 |
Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update | Circulation | 2011 | 554 |
Epidemiology and clinical course of heart failure with preserved ejection fraction | European Journal of Heart Failure | 2011 | 442 |
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling | Cell Metabolism | 2011 | 418 |
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation | Biochemical Journal | 2011 | 273 |
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile | Nature Genetics | 2011 | 237 |
Age-related changes in aortic arch geometry: relationship with proximal aortic function and left ventricular mass and remodeling | Journal of the American College of Cardiology | 2011 | 203 |
Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study | Hypertension | 2011 | 202 |
Overview of Basic Mechanisms of Cardiac Arrhythmia | Cardiac Electrophysiology Clinics | 2011 | 174 |
Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals | Hypertension | 2011 | 154 |
Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms | Diabetes Care | 2011 | 145 |
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells | Journal of Clinical Investigation | 2011 | 144 |
Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore | Journal of Biological Chemistry | 2011 | 138 |
Iron deficiency in blood donors: analysis of enrollment data from the REDS-II Donor Iron Status Evaluation (RISE) study | Transfusion | 2011 | 130 |
Wnt signaling regulates hepatic metabolism | Science Signaling | 2011 | 129 |
Simultaneous measurement of protein oxidation and S-nitrosylation during preconditioning and ischemia/reperfusion injury with resin-assisted capture | Circulation Research | 2011 | 129 |
Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies | Journal of Clinical Endocrinology and Metabolism | 2011 | 114 |
Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom | Circulation | 2011 | 97 |
Multiple loci are associated with white blood cell phenotypes | PLoS Genetics | 2011 | 92 |
BRCA1 is an essential regulator of heart function and survival following myocardial infarction | Nature Communications | 2011 | 89 |
Identifying important risk factors for survival in patient with systolic heart failure using random survival forests | Circulation: Cardiovascular Quality and Outcomes | 2011 | 88 |
S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease | Lipids in Health and Disease | 2011 | 83 |
Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53 | PLoS ONE | 2011 | 80 |
Multi-laboratory evaluations of XMRV nucleic acid detection assays | Retrovirology | 2011 | 78 |